MCM8-9 helicase activity protects primordial germ cell development to prevent premature ovarian insufficiency. [PDF]
Jiao X +5 more
europepmc +1 more source
Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay +4 more
wiley +1 more source
Pathogenic mechanisms and therapeutic potential of the microbiome in premature ovarian insufficiency. [PDF]
Ma S, Zheng L, Zhuang X, Wang M, Zou Y.
europepmc +1 more source
Artificial Intelligence in Medicine: Basic Knowledge, Applications, Ethics and Perspectives
ABSTRACT Background Artificial intelligence (AI) is rapidly transforming medicine through advanced diagnostic, prognostic, and decision‐support systems. Objective To summarize the fundamental concepts, clinical applications, ethical issues, and future perspectives of AI in healthcare.
Marco Cascella +17 more
wiley +1 more source
Novel variants associated with premature ovarian insufficiency in Russian adolescents. [PDF]
Tsabai P +21 more
europepmc +1 more source
Abstract Background Atopic diseases, including atopic dermatitis, allergic rhinitis, and asthma, are complex inflammatory conditions with increasing prevalence in children. Central precocious puberty (CPP) has also become increasingly common. The potential role of CPP in atopic diseases remains unclear.
Yung‐Han Lai +5 more
wiley +1 more source
Protective effect of Zymosan-A against radiation-induced premature ovarian insufficiency in a murine model. [PDF]
Yu Y +8 more
europepmc +1 more source
Abstract Menopause‐related cognitive decline, often worsened by vasomotor symptoms (VMS), might be mitigated by high cardiorespiratory fitness (CRF). Although acute exercise supports neurocognitive function, its effects vary by exercise and individual characteristics.
Morgane Le Bourvellec +4 more
wiley +1 more source
Quercetin ameliorates cyclophosphamide-induced premature ovarian insufficiency by modulating SIRT1/HIF-1α pathway. [PDF]
Wang M +12 more
europepmc +1 more source
Update of the risk assessment on dioxins and dioxin‐like PCBs in feed and food
Abstract The European Commission asked EFSA to update its 2018 risk assessment on polychlorinated dibenzo‐p‐dioxins and dibenzofurans (PCDD/Fs) and dioxin‐like polychlorinated biphenyls (DL‐PCBs) in feed and food, based on the 2022 WHO Toxic Equivalency Factors (WHO2022‐TEFs).
EFSA Panel on Contaminants in the Food Chain (CONTAM Panel) +27 more
wiley +1 more source

