Results 161 to 170 of about 516,689 (292)

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, EarlyView.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

The miR167–ARF8 module coordinates stamen–pistil development and fruit set in tomato

New Phytologist, EarlyView.
SlMIR167a is the functionally prominent SlMIR167 gene in tomato fruit development. Summary Auxin is an important regulator of reproductive development. The families of the AUXIN RESPONSE FACTOR (ARF) genes, important components of the auxin signal, have expanded in flowering plants.
Nave Man, Naama Teboul, Amir Bahu, Moritz Friesch, Alon Israeli, Tzahi Arazi, Bettina Hause, Naomi Ori   +7 more
wiley   +1 more source

Durum Wheat cv. Svevo Reference Genome Rel.2.0: A Comprehensive Tool for Wheat Genomics

Plant Biotechnology Journal, EarlyView.
ABSTRACT Advancements in plant genome sequencing and assembly have enabled the production of increasingly accurate and contiguous genome sequences. Here, we present the chromosome‐level assembly of the durum wheat (Triticum turgidum L. ssp. durum, cv. Svevo) reference genome produced using accurate long‐reads, optical mapping and Hi‐C. The new assembly
Elisabetta Mazzucotelli, Cristian Forestan, Gina Zastrow‐Hayes, David Swarbreck, Yael Lev‐Mirom, Emile Cavalet‐Giorsa, Matteo Bozzoli, Anna Maria Mastrangelo, Daniela Marone, Vincent Ranwez, Johanna Girodolle, Victor Llaca, Kevin Fengler, Charlotte Harris, Helena Toegelová, Pavla Navrátilová, Primetta Faccioli, Francesca Desiderio, Ana Paola Valladares, Gemy Kaithakottil, Rachel L. Rusholme‐Pilcher, Manuel Spannagl, Heidrun Gundlach, Klaus F. X. Mayer, Victoria C. Blake, Justin D. Faris, Steven S. Xu, Taner Z. Sen, Eric Yao, Julio Isidro y Sánchez, Chunyi Liu, Muhammad A. Farooq, Sandra Stefanelli, Chiara Cappucci, Leah Oren, Tamar Eilam, Mario Giorgioni, Alessandra Stella, Barbara Lazzari, Massimiliano Lauria, Aldo Ceriotti, Raul Pirona, Elahe Tavakol, Valentyna Klymiuk, Jennifer Ens, Harmeet Singh Chawla, Sean Walkowiak, Nicola Pecchioni, Filippo M. Bassi, Miguel Sanchez‐Garcia, Gabriella Sonnante, Pasquale L. Curci, Giovanni Giuliano, Giuseppe Aprea, Asher Pasha, Agata Gadaleta, Ilaria Marcotuli, Stefania Masci, Francesco Sestili, Samuela Palombieri, Davide Scaglione, Michele Morgante, Hana Šimková, Nicholas J. Provart, Simon G. Krattinger, Curtis J. Pozniak, Nathalie Chantret, Anthony Hall, Assaf Distelfeld, Roberto Tuberosa, Marco Maccaferri, Luigi Cattivelli   +71 more
wiley   +1 more source

Premature ovarian failure risk factors in an Iranian population

, 2012
Alieh Ghassemzadeh1,2, Laya Farzadi1,2, Elaheh Beyhaghi1,21Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; 2Alzahra University Hospital, Department of Obstetrics and Gynecology, Tabriz ...
Beyhaghi E, Farzadi L, Ghassemzadeh A
core  

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

Limb Compression Therapy and Chemotherapy‐Induced Peripheral Neuropathy in Women With Gynecologic Cancers: A Prospective Self‐Controlled Study(NEURO‐GLOVE Trial)

International Journal of Cancer, Volume 159, Issue 9, Page 2300-2313, 1 November 2026.
With no effective drug‐based prevention strategies available for chemotherapy‐induced peripheral neuropathy (CIPN), research in neuroprotective approaches has grown. Of particular interest is mechanical compression, which may protect nerves by temporarily reducing blood flow during treatment. The authors here conducted a prospective trial in women with
Kadriye Başkurt, Galip Can Uyar, Enes Yeşilbaş, Fatma Zehra Altunç, Damla Erimhan Çevik, İsmet Murat Melek, Yasemin Eren, Ömür Berna Çakmak Öksüzoğlu, Kadriye Bir Yücel, Antonio Di Meglio, Isabelle Ray‐Coquard, Osman Sütcüoğlu   +11 more
wiley   +1 more source

Premature Ovarian Insufficiency: Aetiology and Long-Term Consequences

, 2017
Premature ovarian insufficiency (POI) is characterised by premature cessation of ovulation/menstruation for 4-6 months along with raised serum gonadotropin levels especially folliclestimulating hormone (FSH) (>40 IU/L) on two or more occasions >4 ...
Isha Manesh, MD Student, Naina Kumar, MD
core  

Interaction of FXTAS Family History and College Degree Attainment Predicts Trajectories of Cognitive and Motor Symptoms in FMR1 Premutation Carrier Women

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 7, Page 451-463, October 2026.
ABSTRACT The present longitudinal study focuses on FMR1 premutation carrier women during midlife and early old age (n = 115). Bringing together the genetic risk factor of a family history of FXTAS and the environmental protective factor of higher education, the goal of the study was to determine how these factors potentially interact to predict self ...
Jinkuk Hong, Leann Smith DaWalt, Jessica Klusek, Elizabeth M. Berry‐Kravis, Marsha Mailick   +4 more
wiley   +1 more source

Model‐Enabled Knowledge Transfer Across Cell Lines, Culture Scales and Conditions

Biotechnology and Bioengineering, Volume 123, Issue 10, Page 2613-2628, October 2026.
ABSTRACT Mechanistic models are central to quantitative understanding and optimization of Chinese hamster ovary (CHO) cell culture processes, but their utility is often restricted by parameter sets calibrated for specific cell lines, scales, or operating conditions.
Luxi Yu, Antonio del Rio Chanona, Cleo Kontoravdi   +2 more
wiley   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source