Results 181 to 190 of about 21,624 (243)
Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice
This study shows that oxidative changes in oocytes from aged female mice lead to lipid droplet accumulation and altered energy and retinoid metabolism. These changes persist in embryonic organs, triggering antioxidant responses in lipid‐rich tissues. Remarkably, altered profiles are transmitted across generations, reaching third generation, suggesting ...
Hafsa Gulzar +8 more
wiley +1 more source
Gut virome dysbiosis contributes to premature ovarian insufficiency by modulating gut bacteriome. [PDF]
Jin J +15 more
europepmc +1 more source
Summary Allogeneic haematopoietic stem cell transplantation (ASCT) is a curative treatment for acute myeloid leukaemia (AML) but carries a high risk of gonadotoxicity. Ovarian tissue cryopreservation (OTC) offers a fertility preservation option, yet its safety in AML remains uncertain due to the risk of leukaemic cell reintroduction. The FERTILAM pilot
Augustin Boudry +13 more
wiley +1 more source
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao +7 more
wiley +1 more source
Blepharophimosis, ptosis, and epicanthus inversus [PDF]
De Baere, Elfride, Verdin, Hannah
core +1 more source
Distinct urinary exosomal microRNAs as biomarkers for differentiating premature ovarian insufficiency and menopause. [PDF]
Maham S +5 more
europepmc +1 more source
Invasive breast carcinomas with papillary features (IBCP) comprise diverse subtypes with variable architecture, histopathology, and clinical behaviour. This review outlines evolving classification, diagnostic criteria, and treatment implications, highlighting challenges in distinguishing in situ from invasive lesions. Standardised diagnostic approaches
Emad A Rakha +2 more
wiley +1 more source
Exploring the Experiences and Reproductive Health Needs of Young Women With Premature Ovarian Insufficiency: A Qualitative Content Analysis. [PDF]
Pargar F +4 more
europepmc +1 more source

