Results 181 to 190 of about 21,624 (243)

Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice

open access: yesAging Cell, Volume 25, Issue 3, March 2026.
This study shows that oxidative changes in oocytes from aged female mice lead to lipid droplet accumulation and altered energy and retinoid metabolism. These changes persist in embryonic organs, triggering antioxidant responses in lipid‐rich tissues. Remarkably, altered profiles are transmitted across generations, reaching third generation, suggesting ...
Hafsa Gulzar   +8 more
wiley   +1 more source

Gut virome dysbiosis contributes to premature ovarian insufficiency by modulating gut bacteriome. [PDF]

open access: yesGut Microbes
Jin J   +15 more
europepmc   +1 more source

Current understanding of ovarian aging [PDF]

open access: yes, 2012
Bo Xu   +5 more
core   +1 more source

Assessment of measurable residual disease in ovarian tissue collected for fertility preservation in patients in remission from acute myeloid leukaemia: A pilot study

open access: yesBritish Journal of Haematology, Volume 208, Issue 3, Page 897-904, March 2026.
Summary Allogeneic haematopoietic stem cell transplantation (ASCT) is a curative treatment for acute myeloid leukaemia (AML) but carries a high risk of gonadotoxicity. Ovarian tissue cryopreservation (OTC) offers a fertility preservation option, yet its safety in AML remains uncertain due to the risk of leukaemic cell reintroduction. The FERTILAM pilot
Augustin Boudry   +13 more
wiley   +1 more source

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

open access: yesCell Proliferation, Volume 59, Issue 3, March 2026.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao   +7 more
wiley   +1 more source

Treatment of patients with prolactinomas [PDF]

open access: yes, 1978
Fahlbusch, R.   +5 more
core   +1 more source

The spectrum of breast in situ papillary carcinomas with invasion and invasive breast carcinomas with papillary features: an overview of histological subtypes and diagnostic challenges

open access: yesHistopathology, Volume 88, Issue 4, Page 747-768, March 2026.
Invasive breast carcinomas with papillary features (IBCP) comprise diverse subtypes with variable architecture, histopathology, and clinical behaviour. This review outlines evolving classification, diagnostic criteria, and treatment implications, highlighting challenges in distinguishing in situ from invasive lesions. Standardised diagnostic approaches
Emad A Rakha   +2 more
wiley   +1 more source

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