Dominant follicle-targeted nanocarriers for GH delivery to alleviate premature ovarian insufficiency. [PDF]
Yang S +10 more
europepmc +1 more source
Environmental chemicals and their effects on female reproductive health: Searching for molecular mechanisms and effect biomarkers [PDF]
Johansson, Hanna Katarina Lilith
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IFN-γ and IL-22 in premature ovarian insufficiency correlation with ovarian reserve markers and pathogenic implications: a cross-sectional study. [PDF]
He M +9 more
europepmc +1 more source
HucMSC-derived exosomes alleviate chemotherapy-induced premature ovarian insufficiency via SMURF1-mediated inhibition of ferroptosis in ovarian granulosa cells. [PDF]
Xu B +8 more
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Noninvasive markers for warning premature ovarian insufficiency: a Mendelian randomisation study. [PDF]
Tan H, Zhao J, Wang B, Li Y.
europepmc +1 more source
Loss of p21 does not protect against premature ovarian insufficiency caused by alkylating agents. [PDF]
Lu X +8 more
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Premature ovarian insufficiency
BMJPremature ovarian insufficiency (POI) is a cause of infertility and endocrine dysfunction in women, defined by loss of normal, predictable ovarian activity before the age of 40 years. POI is clinically characterized by amenorrhoea (primary or secondary) with raised circulating levels of follicle-stimulating hormone.
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Premature ovarian insufficiency
Current Opinion in Endocrine and Metabolic Research, 2023Natural menopause typically occurs between the ages of 46 to 55 years. Premature ovarian insufficiency or premature menopause refers to compromised ovarian follicular activity, occurring spontaneously or because of medical interventions, prior to the age of 40 years.
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Premature ovarian insufficiency and infertility
Australian Journal of General Practice, 2023Premature ovarian insufficiency (POI) is the loss of ovarian function before the age of 40 years and can be spontaneous or iatrogenic. It is an important cause of infertility, and the diagnosis should be considered in any woman presenting with oligo/amenorrhoea, even in the absence of menopausal symptoms suchas hot flushes.The aim of this article is to
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