Thyroid Hormone in Women with Premature Ovarian Insufficiency: A Case-Control Study. [PDF]
Zhang Y +6 more
europepmc +1 more source
Cancer survivorship in malignant melanoma
Summary Robust long‐term survival data have transformed the prognosis of metastatic melanoma. For combination therapy with immune checkpoint inhibitors (ICIs), 10‐year melanoma‐specific survival rates now exceed 50 %, and durable disease control is achievable in a substantial proportion of patients, including those with brain metastases.
Markus Reitmajer +15 more
wiley +1 more source
Association of Chemerin, follicle stimulating hormone, lipid profiles, and cardiometabolic indices with the premature ovarian insufficiency. [PDF]
Nikbazm R +5 more
europepmc +1 more source
ABSTRACT Recent studies suggest that variations in milk yield during lactation can serve as a metric for assessing individual resilience, with minimum fluctuations reflecting greater resilience in cows. With automatic milking systems, multiple records can be obtained from many cows on a daily basis. Given that animals are continually exposed to a range
M. Agyiri +7 more
wiley +1 more source
Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
We report a stapled glucagon‐like peptide‐1 (GLP‐1) analogue created via multicomponent tryptophan‐mediated Petasis reaction (TMPR). This strategy yields a stabilised peptide with superior helicity and improved potency. Conjugation to a bromodomain‐containing protein 4 (BRD4) degrader creates the first GLP‐1‐guided targeted protein degrader (PROTAC ...
Jan L. Venne +5 more
wiley +2 more sources
Acupuncture for Premature Ovarian Insufficiency: A Randomized, Non-Inferiority Protocol with Exploratory Epigenetics Analysis. [PDF]
Luo Y +7 more
europepmc +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 10, Page 1834-1836, September 2026.
Ursula Blyth +9 more
wiley +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Gut microbiota-derived butyrate and the SIRT1/FoxO1 axis: epigenetic-metabolic regulation of ovarian function in premature ovarian insufficiency-a comprehensive review. [PDF]
Tian S +5 more
europepmc +1 more source
Treating age‐related loss of muscle mass and function: Where should we be focusing?
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham +4 more
wiley +1 more source

