Persistent Alterations of Brain and Behavior in Children With Low Prenatal Alcohol Exposure. [PDF]
Long X, Lebel C.
europepmc +1 more source
ABSTRACT Familial adenomatous polyposis (FAP) is a hereditary condition marked by the growth of hundreds to thousands of adenomatous polyps in the colon and rectum, significantly elevating the risk of colorectal cancer (CRC) if left untreated. Caused by pathogenic variants in the APC gene, FAP is typically identified in adolescence, often leading to ...
John Gásdal Karstensen
wiley +1 more source
A register-based study of long-term health and social care costs among children with prenatal alcohol exposure. [PDF]
Jolma M +9 more
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Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu +8 more
wiley +1 more source
Knowledge as prevention: A cost-effective intervention to reduce prenatal alcohol exposure. [PDF]
Keating O +4 more
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Maternal anorexia nervosa and risk of mental and neurodevelopmental morbidity in offspring
Background Anorexia nervosa has the potential to affect fetal neurodevelopment. We examined the association between maternal anorexia nervosa and mental, substance‐related, and neurodevelopmental morbidity in offspring. Methods We conducted a retrospective cohort study of 1,269,370 children in Quebec, Canada, between 2006 and 2022.
Sam Amar +8 more
wiley +1 more source
Comparative analysis of test tube and volumetric drinking monitor methods in voluntary ethanol consumption in female mice for prenatal alcohol exposure. [PDF]
Rodriguez AM, Bauer KC, Cunningham LA.
europepmc +1 more source
Making Accurate Judgements in Child Welfare: Comparing ChatGPT With Qualified Social Workers
ABSTRACT This study compares the judgemental accuracy of child and family social workers (n = 581) with ChatGPT, a generative AI model. Using 12 anonymized referrals, participants were asked predictive questions to evaluate accuracy through Brier scores. ChatGPT outperformed the average social worker on 11 of the 12 referrals, though the difference was
David Wilkins, Verity Benett
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Prenatal alcohol exposure increases the aggressiveness of estrogen-induced pituitary tumors in male rats. [PDF]
Chaudhary S, Sarkar DK.
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Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo +6 more
wiley +1 more source

