Liquid Biopsy: Past, Present, and Future
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu +8 more
wiley +1 more source
Prenatal Alcohol Exposure and the Development of Multiple Risk Behaviors in Adolescence: A Birth Cohort Study. [PDF]
Parsonage JTI +4 more
europepmc +1 more source
Abstract Substance use complicates upward of 10% of US pregnancies. The Society for Maternal‐Fetal Medicine, the American College of Obstetricians and Gynecologists, and the American Society of Addiction Medicine have jointly recommended universal screening for substance use during pregnancy using a validated tool, without recommending universal ...
Society for Maternal‐Fetal Medicine (SMFM) +8 more
wiley +1 more source
ACSS2 mediates prenatal alcohol exposure-related morphological and behavioral phenotypes. [PDF]
Dodson KM +11 more
europepmc +1 more source
Association of maternal height with pregnancy complications: Analyses of two cohorts
Abstract Background Height is inversely associated with risk of cardiovascular and metabolic conditions in nonpregnant populations. Whether maternal height is independently associated with pregnancy complications, after accounting for prepregnancy weight, remains less clear.
Ruchi Tiwari +4 more
wiley +1 more source
Does a Biochemical Approach Facilitate the Diagnosis of Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder in Neonatal Period? [PDF]
Jańczewska I +5 more
europepmc +1 more source
Abstract Background Despite providing both maternal and neonatal benefits, breastfeeding rates remain lower than goal targets. Prior observational studies suggest group prenatal care (GPNC) increases breastfeeding initiation compared to individual prenatal care (IPNC), but few randomized controlled trials (RCTs) have examined how GPNC impacts ...
Alexa I. K. Campbell +7 more
wiley +1 more source
Moderate prenatal alcohol exposure differentially alters acute ethanol sensitivity of GABAergic transmission in CRFR1- and CRFR1+ CeM Neurons. [PDF]
Winchester SE, Diaz MR.
europepmc +1 more source
Two‐Stage Estimation for Causal Inference Involving Semi‐Continuous Exposures
ABSTRACT Methods for causal inference are well developed for binary and continuous exposures, but in many settings, the exposure has a substantial mass at zero—such exposures are called semi‐continuous. We propose a general causal framework for such semi‐continuous exposures, together with a two‐stage estimation strategy.
Xiaoya Wang +7 more
wiley +1 more source
Genome Aging in Women: Hematopoietic Loss of X Chromosome as An Exemplar
As studies at the intersection of genetics and aging are rapidly advancing, genome aging provides a novel mechanism by which aging phenotypes occur. In this Review, the authors examine the rise, expansion, and the consequences of X chromosome loss in female blood cells.
Xihan Guo, Xueqin Dai
wiley +1 more source

