Results 171 to 180 of about 84,366 (274)

Familial Adenomatous Polyposis—Risk of Cancer, Cancer Prevention, and Long‐Term Consequences: Learnings from Five Decades with the Danish Polyposis Register

open access: yesAPMIS, Volume 134, Issue 5, May 2026.
ABSTRACT Familial adenomatous polyposis (FAP) is a hereditary condition marked by the growth of hundreds to thousands of adenomatous polyps in the colon and rectum, significantly elevating the risk of colorectal cancer (CRC) if left untreated. Caused by pathogenic variants in the APC gene, FAP is typically identified in adolescence, often leading to ...
John Gásdal Karstensen
wiley   +1 more source

A register-based study of long-term health and social care costs among children with prenatal alcohol exposure. [PDF]

open access: yesPLoS One
Jolma M   +9 more
europepmc   +1 more source

Maternal exercise improves vascular function in hypertensive offspring via A‐kinase anchoring protein 150 gene (Akap5) epigenetic modifications

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2592-2612, May 2026.
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu   +8 more
wiley   +1 more source

Knowledge as prevention: A cost-effective intervention to reduce prenatal alcohol exposure. [PDF]

open access: yesAlcohol Clin Exp Res (Hoboken)
Keating O   +4 more
europepmc   +1 more source

Maternal anorexia nervosa and risk of mental and neurodevelopmental morbidity in offspring

open access: yesChild and Adolescent Mental Health, Volume 31, Issue 2, Page 125-133, May 2026.
Background Anorexia nervosa has the potential to affect fetal neurodevelopment. We examined the association between maternal anorexia nervosa and mental, substance‐related, and neurodevelopmental morbidity in offspring. Methods We conducted a retrospective cohort study of 1,269,370 children in Quebec, Canada, between 2006 and 2022.
Sam Amar   +8 more
wiley   +1 more source

Making Accurate Judgements in Child Welfare: Comparing ChatGPT With Qualified Social Workers

open access: yesChild &Family Social Work, Volume 31, Issue 2, Page 703-712, May 2026.
ABSTRACT This study compares the judgemental accuracy of child and family social workers (n = 581) with ChatGPT, a generative AI model. Using 12 anonymized referrals, participants were asked predictive questions to evaluate accuracy through Brier scores. ChatGPT outperformed the average social worker on 11 of the 12 referrals, though the difference was
David Wilkins, Verity Benett
wiley   +1 more source

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

open access: yesCell Proliferation, Volume 59, Issue 5, May 2026.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo   +6 more
wiley   +1 more source

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