Results 31 to 40 of about 30,850 (274)

Maternal drinking behavior and Fetal Alcohol Spectrum Disorders in adolescents with criminal behavior in southern Brazil

open access: yesGenetics and Molecular Biology, 2012
Prenatal alcohol exposure can have serious and permanent adverse effects. The developing brain is the most vulnerable organ to the insults of prenatal alcohol exposure.
Wakana Momino   +8 more
doaj   +1 more source

Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview

open access: yesFrontiers in Pediatrics, 2020
Prenatal alcohol exposure is associated to different physical, behavioral, cognitive, and neurological impairments collectively known as fetal alcohol spectrum disorder.
Laura Almeida   +20 more
doaj   +1 more source

The association between neighborhood environment, prenatal exposure to alcohol and tobacco, and structural brain development

open access: yesFrontiers in Human Neuroscience
Prenatal alcohol and tobacco exposure affects child brain development. Less is known about how neighborhood environment (built, institutional, and social) may be associated with structural brain development and whether prenatal exposure to alcohol or ...
Yingjing Xia, Verónica M. Vieira
doaj   +1 more source

The effect of prenatal alcohol exposure (PAE) on the onset of speech disorders and communication problems in children and adolescents

open access: yesJournal of Education, Health and Sport, 2022
Alcohol consumption has many negative effects on the human body, and has been proven to have teratogenic effects on fetal development. Prenatal alcohol exposure (PAE) is associated with growth deficits and neurodevelopmental disorders, including fetal ...
Anna Gryc   +4 more
doaj   +1 more source

Neurotoxicity of prenatal alcohol exposure on medullary pre-Bötzinger complex neurons in neonatal rats

open access: yesNeural Regeneration Research, 2015
Prenatal alcohol exposure disrupts the development of normal fetal respiratory function, but whether it perturbs respiratory rhythmical discharge activity is unclear.
Ming-li Ji, Yun-hong Wu, Zhi-bin Qian
doaj   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

Prenatal exposure to alcohol does not affect radial maze learning and hippocampal mossy fiber sizes in three inbred strains of mouse

open access: yesBehavioral and Brain Functions, 2005
Background The aim of this study was to investigate the effects of prenatal alcohol exposure on radial-maze learning and hippocampal neuroanatomy, particularly the sizes of the intra- and infrapyramidal mossy fiber (IIPMF) terminal fields, in three ...
Bertholet Jean-Yves   +3 more
doaj   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

open access: yesAdvanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu   +13 more
wiley   +1 more source

Alcohol consumption among pregnant women in James Town Community, Accra, Ghana

open access: yesReproductive Health, 2017
Background Alcohol consumption among pregnant women is a public health concern, considering its adverse outcomes for both mother and the developing foetus.
Joanita Da Pilma Lekettey   +3 more
doaj   +1 more source

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

open access: yesAdvanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han   +16 more
wiley   +1 more source

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