Results 71 to 80 of about 1,912,395 (308)
Reproductive Health, 2020 Introduction This study analyze factors associated to cannabis use in pregnant women, its perceived availability, its risk perception and the relationship between prenatal exposure to cannabis and developmental and mental disorders. Objectives We present
Carlos Roncero +5 more
doaj +1 more source
Drug Repurposing for Treating NCOR‐Related Intellectual Disability
Advanced Science, EarlyView.An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong +15 more
wiley +1 more source
Exploring language production, comprehension and naming in adolescents with fetal alcohol spectrum disorders [PDF]
, 2011 The aims of this study were i) to evaluate the domains of language production, comprehension and naming in children with moderate or heavy prenatal exposure to alcohol, and ii) to determine if these domains are a specific weakness in these children.
Corbett, Claire
core +1 more source
An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula +8 more
wiley +1 more source
Prenatal methadone exposure and the developing brain [PDF]
, 2019 Opioid use globally is increasing resulting in rising numbers of pregnant women exposing their unborn babies to opioid drugs, with an estimated 30,000 children each year in Europe born to mothers who have used opioids during pregnancy.
Monnelly, Victoria J.
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto +5 more
wiley +1 more source
Delayed Recognition of Maternal G6PD Heterozygous Status Across Prenatal and Newborn Care Interfaces
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is the most common red blood cell enzymatic disorder worldwide. Although many heterozygotes are asymptomatic, affected neonates have an increased risk for hyperbilirubinemia and related complications.
Mona M. Makhamreh +5 more
wiley +1 more source
Aggressive behavior in adolescents with fetal alcohol spectrum disorders [PDF]
, 2013 Includes bibliographical references.Behavioral studies of fetal alcohol spectrum disorders (FASD) have indicated that aggression is common amongst alcohol-exposed adolescents, and that it appears to become more prevalent with age in that population. Such
Smith, Keelie
core +1 more source
Brain and BehaviorIntroduction Prenatal substance exposure is an increasing problem that has been linked to multiple neurodevelopmental impairments and alterations to brain functional connectivity.
Ramana V. Vishnubhotla +2 more
doaj +1 more source
Prenatal environmental tobacco smoke exposure: a predictor of blood selenium levels in children
Frontiers in Public HealthIntroductionThe aim of the study was to investigate the relationship between prenatal environmental tobacco smoke (ETS) exposure and blood selenium concentration (Se-B) in a selected group of children.MethodsA total of 299 children were recruited for ...
Paweł Gać +5 more
doaj +1 more source