Results 41 to 50 of about 3,822 (129)

Psychotropic medication and the fetal brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley   +1 more source

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Asthma in Children With Congenital Lung Malformations: A Population‐Based Case‐Control Study

open access: yesPediatric Pulmonology, Volume 61, Issue 7, July 2026.
ABSTRACT Background Congenital lung malformations (CLM) are developmental anomalies that may predispose to respiratory morbidity. Their association with asthma remains unclear, largely due to small series and the lack of population‐based controls. Objective To evaluate asthma prevalence and related outcomes in children with CLM compared to population ...
Louis W. J. Dossche   +6 more
wiley   +1 more source

Nicotine Exposure During Pregnancy and Postnatal Cognitive Outcomes: A Systematic Review and Meta‐Analysis

open access: yesActa Paediatrica, Volume 115, Issue 7, Page 1413-1428, July 2026.
ABSTRACT Aim Nicotine exposure during pregnancy interferes with critical periods of foetal brain development, disrupting the timing and functioning of neurodevelopment. This systematic review and meta‐analysis aims to evaluate the effect of prenatal nicotine exposure on postnatal cognitive outcomes.
Deimantė Baguckaitė   +2 more
wiley   +1 more source

Dissecting the polygenic architecture of psychopathology via singular value decomposition of eight psychiatric genome‐wide association studies and evaluation of component‐based polygenic scores

open access: yesGeneral Psychiatry, Volume 39, Issue 3, June 2026.
ABSTRACT Background Current research suggests that genetic risk for psychiatric disorders is largely due to distinct combinations of many common variants shared by different disorders. This points to the existence of latent components affecting different dimensions of psychopathology.
Fernando Facal   +2 more
wiley   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

open access: yesPhytochemical Analysis, Volume 37, Issue 4, Page 507-535, June 2026.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek   +3 more
wiley   +1 more source

Examining buprenorphine compared to methadone for likelihood of overdose during pregnancy, 2014–2021

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Objective To examine the likelihood of experiencing an overdose among women receiving any buprenorphine (with or without naloxone) compared to women receiving methadone during pregnancy. Methods Data from the MATernaL and Infant clinical NetworK (MAT‐LINK), a longitudinal surveillance system of pregnant woman–child dyads using electronic ...
Amy Board   +20 more
wiley   +1 more source

Clinical Presentation and Management of PHACE Syndrome in a Pediatric Patient

open access: yesCiencia y Salud
Introduction PHACE syndrome is a rare neurocutaneous disorder characterized by posterior fossa malformations, hemangiomas, arterial anomalies, cardiac defects, and ocular abnormalities.
Christy Capestany   +3 more
doaj   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

Usability and Acceptability of a Pregnancy App for Substance Use Screening and Education: A Mixed Methods Exploratory Pilot Study

open access: yesJMIR Pediatrics and Parenting
BackgroundIncreasing opioid and other substance use has led to a crisis of epidemic proportions, with substance use now recognized as a leading cause of maternal morbidity and mortality in the United States.
Haley Fitzgerald   +4 more
doaj   +1 more source

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