Results 121 to 130 of about 3,960 (214)

A Fungal Promiscuous UbiA Prenyltransferase Expands the Structural Diversity of Chrodrimanin-Type Meroterpenoids

Prenyltransferases play important roles in the diversification of natural products and the improvement of biological activities. A UbiA-type prenyltransferase CdnC with substrate promiscuity was identified as the pivotal builder of the noncanonical ...
Chuanteng Ma (10163706), Kaijin Zhang (8352042), Dehai Li (1433623), Tianjiao Zhu (1433617), Qian Che (725671), Junyu Liu (479315), Guojian Zhang (1604386), Xuewen Hou (3525002)   +7 more
core   +1 more source

Identification and specificity profiling of protein prenyltransferase inhibitors using new fluorescent phosphoisoprenoids

, 2006
Posttranslational modification of proteins with farnesyl and geranylgeranyl isoprenoids is a widespread phenomenon in eukaryotic organisms. Isoprenylation is conferred by three protein prenyltransferases: farnesyl transferase (FTase), geranylgeranyl ...
Delon, Christine, Alexandrov, K., Dursina, Beatrice, Waldmann, Herbert, Veligodsky, Alexei, Alexandrov, Kirill, Kalinin, A., Szedlacsek, Stefan, E., Kulharia, M., Veligodsky, A., Thutewohl, M., Wu, Y., Ciobanu, D., Goody, Roger, S., Goody, R., Kulharia, Mahesh, Szedlacsek, S., Waldmann, H., Thutewohl, Michael, Wu, Yaowen, W., Evstifeev, Vladimir, Reents, R., Ciobanu, Doina, Kalinin, Alexandr, Evstifeev, V., Reents, Reinhard, Dursina, B., Delon, C.   +27 more
core   +1 more source

Geranylation of Chalcones by a Fungal Aromatic Prenyltransferase

Geranylated chalcones mainly exist in plants, and many of them have attracted attention because of their diverse pharmacological and biological activities.
Song Yang (162335), Kang Zhou (122652), Linlan Tao (14309701), Chun-Mao Yuan (1475944), Qianqian Ran (14768310), Xiang Zhou (164107), Shu-Ming Li (1523233)   +6 more
core   +1 more source

Characterization and structural analysis of a versatile aromatic prenyltransferase for imidazole-containing diketopiperazines

Nature Communications
Prenylation modifications of natural products play essential roles in chemical diversity and bioactivities, but imidazole modification prenyltransferases are not well investigated.
Wenxue Wang, Peng Wang, Chuanteng Ma, Kang Li, Zian Wang, Yuting Liu, Lu Wang, Guojian Zhang, Qian Che, Tianjiao Zhu, Yuzhong Zhang, Dehai Li   +11 more
doaj   +1 more source

Draft genome sequence of the peptaibol producer <i>Trichoderma asperellum</i> TRC-03. [PDF]

Microbiol Resour Announc
Alfaro-Vargas P, Wicki-Emmenegger D, Mesén-Porras E, Vargas-Chacón C, Bravo Bonilla O, Chaverri P, Chavarría M.   +6 more
europepmc   +1 more source

Cryo-EM Structure of the Cyclase Domain and Evaluation of Substrate Channeling in a Bifunctional Class II Terpene Synthase. [PDF]

Biochemistry
Gaynes MN, Schultz K, Wenger ES, Ronnebaum TA, Marmorstein R, Christianson DW.   +5 more
europepmc   +1 more source

Cell-Free Synthesis of Cannabistilbene I: A Dual Acting Anti-Inflammatory from <i>Cannabis sativa</i>. [PDF]

J Nat Prod
Boddington KF, Soubeyrand E, Van Gelder K, Perrin C, Forrester TJB, Holborn J, Casaretto JA, Al-Abdul-Wahid MS, Piotrowski ML, Magolan J, Lalonde J, Kimber MS, Rothstein SJ, Akhtar TA.   +13 more
europepmc   +1 more source

Elucidation of the Verrucofortine Biosynthetic Pathway Enables Identification of a Cyclodipeptide Prenyltransferase with High Catalytic Efficiency. [PDF]

J Agric Food Chem
Wei HL, Pang LD, Chen XL, Li SM.
europepmc   +1 more source

A Fungal <i>p</i>-Terphenyl Prenyltransferase for Regioselective <i>C</i>-Prenylation of Flavonoids and Other Compounds Bearing <i>ortho</i>-Dihydroxyphenyl Moieties. [PDF]

J Agric Food Chem
Janzen DJ, Zhou J, Losert S, Li SM.
europepmc   +1 more source

Creation of bioactive non-natural flavonoids via combinatorial prenylation-glycosylation cascades. [PDF]

mLife
Zhang H, Zhang A, Ji J, Yin WB.
europepmc   +1 more source