Results 71 to 80 of about 617,401 (307)

Postdoc prep [PDF]

Nature, 2006
Jabbar, Bennett, Cherie, Butts
openaire   +2 more sources

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

Advanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner, Raith Nowak, Stephanie M. Kronstadt, Nicholas H. Pirolli, Talia J. Solomon, Kristin Nikolov, William Pieper Holeman, Ian M. Smith, Kimberly M. Stroka, John P. Fisher, Steven M. Jay   +10 more
wiley   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

A research alliance

Medicine Anthropology Theory, 2017
This article explores a research alliance across fields and continents in the wake of the early and controversial HIV-prevention clinical trials of pre-exposure prophylaxis (PrEP).
Kristin Peterson, Morenike Folayan
doaj   +1 more source

Characteristics of a cohort of high-risk men who have sex with men on pre-exposure prophylaxis reporting transgender sexual partners. [PDF]

, 2019
Transgender people continue to be at high-risk for HIV acquisition, but little is known about the characteristics of their sexual partners. To address this gap, we examined sociodemographic and sexual characteristics of cisgender men who have sex with ...
Blumenthal, Jill S, Corado, Katya, Dube, Michael P, Ellorin, Eric, Hassan, Adiba, Moore, David J, Morris, Sheldon R, Wertheim, Joel O   +7 more
core  

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Setting up a pharmacy HIV pre-exposure prophylaxis delivery model: Lessons and recommendations for implementation

Southern African Journal of HIV Medicine
No abstract available.
Tsitsi Nyamuzihwa, Kelechi E. Oladimeji, Athini Nyatela, Lettie Makola, Samanta T. Lalla-Edward, Angela Tembo   +5 more
doaj   +1 more source

Shoreland and Riparian Buffer Regulations for the Town of Raymond PREP Local Grants Program 2008 Final Project Report [PDF]

, 2010
In September of 2007, SNHPC applied to PREP’s Local Grant Program seeking $5,000 to help develop local shoreland protection ordinances consistent with the state’s Comprehensive Shoreland Protection Act regulations.
Southern New Hampshire Planning Commission, Town of Raymond, New Hampshire   +1 more
core   +2 more sources

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Shellfish Tissue Monitoring in Piscataqua Region Estuaries 2010 and 2011 [PDF]

, 2012
The goal of this project was to provide data for two PREP indicators of estuarine condition: TOX1 and TOX3. These two indicators report on “Shellfish tissue concentrations relative to FDA standards” and “Trends in shellfish tissue contaminant ...
New Hampshire Department of Environmental Services, Trowbridge, Philip R., Wood, Matthew A.   +2 more
core   +2 more sources