Results 71 to 80 of about 257,990 (304)
A PROTAC‐functionalized protein/DNA‐integrated nanoantigen platform is developed to enhance dendritic cell vaccine potency. By combining a VHL‐recruiting peptide‐modified antigen with a sustained expression plasmid within CaCO3 nanoparticles, this system amplifies cross‐presentation, promotes DC maturation, and elicits robust Th1 and CTL responses ...
Peng Liu +4 more
wiley +1 more source
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song +9 more
wiley +1 more source
La profilaxis pre-exposición (PrEp) en la infección por VIH: Un nuevo hito en una carrera de fondo
Dentro del manejo clínico de las personas que viven con el virus de la inmunodeficiencia humana (VIH) y de la prevención de la transmisión del mismo, que aún hoy supone un importante problema de salud pública, la profilaxis pre-exposición (PrEP ...
Emilio Manuel Paez Guillán +1 more
doaj +1 more source
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song +9 more
wiley +1 more source
PURPOSE: To develop a motion-corrected 3D flow-insensitive imaging approach interleaved T2 prepared-inversion recovery (iT2 prep-IR) for simultaneous lumen and wall visualization of the great thoracic vessels and cardiac structures.METHODS: A 3D flow ...
Giulia Ginami +17 more
core +1 more source
Priority area 10—A BCW analysis of ‘PrEP users stop using PrEP’.
Priority area 10—A BCW analysis of ‘PrEP users stop using PrEP’.
Dan Clutterbuck (17118236) +10 more
core +1 more source
Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen +6 more
wiley +1 more source
A picture of Saint Peter's Prep taken from the side of Grand Street.
Founded in 1872 by the Jesuits, Saint Peter's Preparatory School (also known as Saint Peter's Prep or simply Prep) is an independent, preparatory, and all-male day school located in Jersey City.
Beards, Daniel E.
core +1 more source
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu +10 more
wiley +1 more source

