Results 81 to 90 of about 647,081 (351)

Considerații în legătură cu unele termene din cadrul procedurii prealabile sesizării instanței de contencios administrativ

Revista Transilvană de Ştiinţe Administrative, 1999
Legea nr. 29/19901 reglementează o procedură prealabilă sesizării instanţei, care este formată din două etape distincte: prima dintre ele, recursul graţios la autoritatea administrativ emitentă a actului atacat este obligatorie, fiind o condiţie necesară
Dacian DRAGOŞ
doaj  

Improving the Patient Colonoscopy Prep Experience [PDF]

, 2017
AIM: To improve patient prep compliance, prep quality, and an overall better experience by designing a prep specific website that will address the most common prep questions and concerns Once launched, the website address will be placed on printed ...
Cohen, MD, Robert, Cosgrove, MD, Natalie, Dargan, MD, Andrew, Dhanekula, MD, Raja K., Francis, MD, Gloria, Gandhi, MD, Komal, Kistler, MD, Andrew, Malamood, MD, Mark, Moleski, MD, Stephanie M., Niu, MD, Bolin, Prieto, MD, Jorge, Reddy, MD, Sheela S., Shah, MD, Apeksha, Tofani, MD, Christina, Zabolotsky, MD, Andrew   +14 more
core   +1 more source

Experiences of oral pre-exposure prophylaxis (PrEP) use disclosure among South African adolescent girls and young women and its perceived impact on adherence

PLoS ONE, 2021
Introduction There is limited understanding of how social dynamics impact pre-exposure prophylaxis (PrEP) adherence among adolescent girls and young women (AGYW) in generalized HIV-epidemic settings. We examined experiences of oral PrEP use disclosure to
D. Giovenco, K. Gill, Lauren Fynn, Menna Duyver, Shannon O’Rourke, A. van der Straten, J. Morton, C. Celum, L. Bekker   +8 more
semanticscholar   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Despre rezistența la schimbare

Revista Transilvană de Ştiinţe Administrative, 1999
“Bolnavii care suferă de sindromul Down nu pot învăţa să scrie sau să citească niciodată.” Toată lumea crede (mai bine spus, credea) că această afirmaţie este un adevăr indiscutabil. Până când unul dintre persoanele suferind de acest sindrom, neştiind că
Ciprian TRIPON, Călin GHIOLȚAN
doaj  

How Has HIV Pre-Exposure Prophylaxis (PrEP) Changed Sex? A Review of Research in a New Era of Bio-behavioral HIV Prevention

Journal of Sex Research, 2021
In 2012, the U.S. FDA approved the first drug for use as HIV Pre-Exposure Prophylaxis (PrEP), which is nearly 99% effective when taken as prescribed. Although the manifest function of PrEP is to prevent HIV infection in the event of exposure, the drug ...
Christian Grov, D. Westmoreland, Alexa B. D’Angelo, David W. Pantalone   +3 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Real-Time Monitoring and Point-of-Care Testing: A Review of the Current Landscape of PrEP Adherence Monitoring

Patient Preference and Adherence, 2021
Alisse Hannaford,1 Yotam Arens,2 Helen Koenig2 1Department of Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA; 2Division of Infectious Diseases, Hospital of the University of Pennsylvania, Philadelphia, PA ...
Hannaford A, Arens Y, Koenig H
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Current Perspectives on the Impact of Pre-Exposure Prophylaxis Stigma Regarding Men Who Have Sex with Men in the United States

HIV/AIDS: Research and Palliative Care, 2020
Patrick D Herron Department of Family and Social Medicine, Albert Einstein College of Medicine, Bronx, NY, USACorrespondence: Patrick D Herron Email patrick.herron@einsteinmed.orgAbstract: Pre-exposure prophylaxis or PrEP is a Food and Drug ...
Herron PD
doaj