Results 121 to 130 of about 35,813,844 (294)

Study on the preparation process and quality standard of Ji Shenqi anti-cancer granules

Guangxi Yike Daxue xuebao
Objective To preliminarily screen the preparation process of Ji Shenqi anti-cancer granules (JSQ) and establish the quality standard. Methods The excipient types were examined and the formulation moulding process was preferred using the soft material ...
LI Liang, WU Huafeng, HE Bizuan, PANG Liangcheng, QIN Jiuyun, TONG Jianjun, TANG Meihua, JIANG Weizhe, FU Shujie   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

PROCESS FOR THE PREPARATION OF PROPOFOL

, 2023
The present provides a simple, convenient and time-efficient process for the preparation of propofol. Particularly, the present invention provides an improved process for the preparation of propofol using a heterocyclic base for the decarboxylation ...
Saswata Lahiri, Walter Cabri, Sarbiot Singh Sokhi, Govind Singh, Ashvani Kumar, Abhishek Giri   +5 more
core   +1 more source

Preparation, Structural Characterization and Digestive Properties of Zinc Chelates of Takifugu rubripes Bone Collagen Peptide

Shipin gongye ke-ji
In order to develop a novel zinc supplement and broaden the application field of redfin puffer, in this study, redfin oriental leatherback fish bone was used as raw material and ZnSO4·7H2O as zinc source.
Lei HUANG, Jilu SUN, Juntian GAN, Fanyu WANG, Caixuan ZHANG, Hai'en ZHANG, Mingzhu GUO   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The process engraver's monthly.

Numbering continuous.Mode of access: Internet.Feb.-Aug. 1895, 1899- , Nov. 1903, The Process photogram; Apr. 1896-Feb. 1898, The Process photogram and illustrator (continued as caption title to Nov.
Federation of Master Process Engravers.
core  

The Current Development Status in Accelerator Preparation of Radionuclide 68Ge

Journal of Isotopes
In recent years，the PET imaging with 68Ga-labeled radiopharmaceuticals have grown significantly，which is driven by the popularity of 68Ge-68Ga generator，the development of targeted tracers，simple labeling procedures，and approval of 68Ga-labeled ...
Ziyu ZHAO, Chengwei MA, Kai WEN, Fei DUAN, Haomiao CHU, Guang LI   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source