Results 111 to 120 of about 35,813,844 (294)

Ferritin-armed extracellular vesicles with enhanced BBB penetration and tumor-targeting ability for synergistic therapy against glioblastoma

open access: yesJournal of Nanobiotechnology
Glioblastoma multiforme (GBM) is an aggressive brain cancer with a high mortality rate and limited treatment options. Metabolism-based synergistic therapy holds promise for GBM treatment, however, its efficacy is significantly impeded by poor blood-brain
Guihong Lu   +6 more
doaj   +1 more source

Effects of preparation process on performance of rubber modified asphalt

open access: yes, 2015
The rational utilization of waste rubber tire is essential for the environmental protection. Utilizing rubber particles to modify asphalt can not only improve asphalt performance, but also help the recycling of waste materials.
Han-Bing Liu   +3 more
semanticscholar   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The Useful Elements of Pre-principalship Preparation [PDF]

open access: yes, 2007
The importance of the role of the principal in good schools is acknowledged by many sources. The preparation of new principals is therefore an important factor in ensuring children are educated in good schools.
Roberts, Barry Llewellyn
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Arraysets preparation process.

open access: yes, 2015
Arraysets preparation process.
Kornel Chrominski (752166)   +1 more
core   +1 more source

Sustained release PLGA microspheres loaded with a bone-affinity Bmp2 enhance fracture healing and mitigate heterotopic ossification

open access: yesBioactive Materials
Bone morphogenetic protein 2 (Bmp2), an FDA-approved osteogenic factor, demonstrates notable potential for enhancing bone regeneration under challenging conditions such as osteoporotic fractures.
Pengcheng Ren   +7 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

International perspectives on coal preparation [PDF]

open access: yes, 1997
The report consists of the vugraphs from the presentations which covered the following topics: Summaries of the US Department of Energy`s coal preparation research programs; Preparation trends in Russia; South African coal preparation developments ...

core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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