Results 101 to 110 of about 35,813,844 (294)
Binary peptide coacervates as an active model for biomolecular condensates
Nature CommunicationsBiomolecular condensates formed by proteins and nucleic acids are critical for cellular processes. Macromolecule-based coacervate droplets formed by liquid-liquid phase separation serve as synthetic analogues, but are limited by complex compositions and ...
Shoupeng Cao +6 more
doaj +1 more source
PharmaceuticsBackground: With the evolving paradigm of vaccine development, microcapsules have attracted considerable research interest as particulate adjuvants over the past decades.
Shaoyu Guan +7 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Cell Reports MedicineSummary: Oxidative damage and neuroinflammation are the key features of central nervous system (CNS) injury. Inspired by the neuroprotective properties of neural stem cell-derived exosomes (NExo) and the reactive oxygen species (ROS) scavenging ability ...
Wenjing Wang +15 more
doaj +1 more source
Global Truck Production – The Importance of Having a Robust Manufacturing Preparation Process
, 2016 Global production networks (GPN) are generally hard to manage due to spread of processes and systems. The amount of product variants adds to the complexity.
P. Johansson +4 more
semanticscholar +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Design For Gathering People: Seven Planning Process
, 1993 152 hlm.; ill.; 30 ...
PROCESS ARCHITECTURE 113
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Bioactive MaterialsReactive oxygen species (ROS)-mediated oxidative stress exacerbates chronic diseases such as organ damage and neurodegenerative disorders. The Keap1-Nrf2-ARE pathway is a widely distributed endogenous antioxidant system.
Zhiguo Lu +14 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Process Antifoulants for Energy Conservation in the '80's
, 1982 Specialty chemical treatments and related services have been used for may years to enhance the efficiency of industrial processes. In particular, this paper relates to the use of proprietary antifoulants and associated technology to inhibit the formation
Freeman, R. F. +2 more
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