Analytical and Preparative Separation of Softwood Lignans by Supercritical Fluid Chromatography
Lignans are widespread polyphenolic secondary plant metabolites possessing high biological activity. One of the most promising industrial-scale sources of such compounds is coniferous knotwood, containing a large number of polyphenolic compounds.
Nikolay V. Ul’yanovskii +5 more
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Analytical and preparative separation of phosphorothioated oligonucleotides: columns and ion-pair reagents. [PDF]
Oligonucleotide drugs represent an emerging area in the pharmaceutical industry. Solid-phase synthesis generates many structurally closely related impurities, making efficient separation systems for purification and analysis a key challenge during ...
Enmark M +7 more
europepmc +2 more sources
High-speed counter-current chromatography (HSCCC) was successively applied to the separation of three sulfur-containing diketopiperazines (DKPs) (including two new compounds cladosporin A (1) and cladosporin B (3), and a known compound haematocin (2 ...
Binbin Gu +9 more
doaj +2 more sources
One-Step Preparative Separation of Phytosterols from Edible Brown Seaweed Sargassum horneri by High-Speed Countercurrent Chromatography. [PDF]
Sargassum horneri, a sargassaceae brown alga, is one of the main species in the subtidal seaweeds flora extensively distributed in the Yellow and East China Sea. It has been proven that the phytosterols are an important class of bioactive substances in S.
Xia M, Liu C, Gao L, Lu Y.
europepmc +2 more sources
Chiral Separations in Preparative Scale: A Medicinal Chemistry Point of View
Enantiomeric separation is a key step in the development of a new chiral drug. Preparative liquid chromatography (LC) continues to be the technique of choice either during the drug discovery process, to achieve a few milligrams, or to a scale-up during ...
Madalena M.M. Pinto +2 more
doaj +1 more source
Preparative Separation and Purification of the Total Flavonoids in Scorzonera austriaca with Macroporous Resins. [PDF]
The use of macroporous resins for the separation and purification of total flavonoids to obtain high-purity total flavonoids from Scorzonera austriaca was studied. The optimal conditions for separation and purification of total flavonoids in S. austriaca
Xie Y, Guo QS, Wang GS.
europepmc +2 more sources
ISOLASI LISOZIM ALBUMIN TELUR AYAM RAS DENGAN METODE KROMATOGRAFI PENUKAR ION
Lysozyme is one of the proteins found in hen egg albumin. Besides known as antimicrobial agents, lysozyme hydrolysis products can also function as antioxidants and as angiotensin converting enzyme (ACE) inhibitors.
Zakiah Wulandari +4 more
doaj +1 more source
Fast preparative isoelectric focusing of phycocyanin subunits in layers of granulated gels [PDF]
A new method is presented for the fast preparative separation of the light-harvesting photosynthetic pigment C-phycocanin into its and subunits, which is based on isoelectric focusing in layers of granutaled gels containing 7 M urea. The method has been
Fischer, Richard +5 more
core +1 more source
In the countercurrent chromatography and centrifugal partition chromatography, separation method transfer and scale-up is often described as an easy and straightforward procedure.
Simon Roehrer, Mirjana Minceva
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Optimization of Automatic Synthesis and Separation of [18F] AV-45 and Quality Control
Objective: Based on the Tracerlab FXF-N platform, a synthesis program and preparative high-performance liquid chromatography (HPLC) purification program edited by us can stably and repeatedly produce [18F] AV-45 without changing the process. The [18F] AV-
Qi-Zhou Zhang +5 more
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