Results 91 to 100 of about 990,733 (166)

Yi-Gan San Restores Behavioral Alterations and a Decrease of Brain Glutathione Level in a Mouse Model of Schizophrenia

open access: yesJournal of Central Nervous System Disease, 2009
The traditional Chinese herbal medicine yi-gan san has been used to cure neuropsychological disorders. Schizophrenia can be one of the target diseases of yi-gan san.
Manabu Makinodan M.D.   +7 more
doaj   +1 more source

Prepulse Inhibition and Emotion: A Systematic Review

open access: yes
Prepulse inhibition is a neurological pre-conscious sensorimotor gating mechanism by which a softer auditory sound (or prepulse) preceding a startle probe (or pulse) and subsequently reduce the magnitude of the startle blink reflex.
Le, Jennifer U.
core  

Startle response and prepulse inhibition in GluD1-KO mice.

open access: yes, 2020
(A) Acoustic startle response test: Startle responses amplitudes were dependent on pulse intensity (WT, n = 7; GluD1-KO, n = 9) (two-way ANOVA: F7,112 = 24.2, p 1,112 = 0.08, p = 0.78), and no interaction between genotype and tone intensity (F7,112 = 0 ...
Chihiro Nakamoto (8474175)   +8 more
core   +1 more source

Radiation Effects on Dopamine-Mediated Prepulse Inhibition in the C57BL/6 Mouse [PDF]

open access: yes, 2003
This study examined the effects of proton and gamma radiation on a dopamine-dependent sensory gating mechanism: prepulse inhibition of the startle reflex.
Zuccarelli Miller, Cara Nicole
core   +1 more source

Prepulse inhibition of startle-induced reductions of accumbens dopamine [Abstract]

open access: yes, 1995
Schizophrenia patients exhibit deficits in the prepulse inhibition of startle, an operational measure of the sensorimotor gating dysfunctions that may contribute to cognitive disorganization. In rats, activation of mesolimbic dopamine (DA) receptors (e.g.
Wilkinson, Lawrence Stephen   +3 more
core   +1 more source

Involvement of the medial geniculate body in prepulse inhibition of acoustic startle

open access: yes, 1999
Prepulse inhibition of acoustic startle is the normal reduction in startle response to an intense auditory stimulus when this stimulus is immediately preceded by a weaker prestimulus.
Engel, Jörgen,   +3 more
core  

Vestibular prepulse inhibition of the human blink reflex

open access: yes
OBJECTIVE: Auditory and somatosensory prepulses are commonly used to assess prepulse inhibition (PPI). The effect of a vestibular prepulse upon blink reflex excitability has not been hitherto assessed.
Mahmud, Mohammad   +5 more
core   +1 more source

Neonatal viral brain infection and the development of prepulse inhibition : a neurodevelopmental model of schizophrenia [PDF]

open access: yes, 2003
Epidemiological data suggest an important role of perinatal viral infections in the etiology of schizophrenia. In this thesis the connection between neonatal viral brain infection and its consequences to the development of central nervous system was ...
Aitta-aho, Teemu
core  

Prepulse inhibition of the startle response and radioligand binding assays

open access: yes, 2014
Dataset 1. PPI data.The percent PPI data is provided for each prepulse decibel level tested. This raw behavioral data reflects the percentage of inhibition in prepulse-pulse trials compared with pulse-only trials for each prepulse intensity tested.
Jerry Skefos (526825)   +7 more
core   +1 more source

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

open access: yesNeuropsychopharmacology Reports
GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a G protein‐coupled receptor (GPCR), can function as a receptor for l‐3,4‐dihydroxyphenylalanine (DOPA), a precursor of dopamine (DA).
Yoshio Goshima   +9 more
doaj   +1 more source

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