Results 81 to 90 of about 990,733 (166)

Selective nucleus accumbens core lesions enhance dizocilpine-induced but not apomorphine-induced disruption of prepulse inhibition in rats.

, 2006
Prepulse inhibition refers to the reduction in startle reaction to a startle-eliciting 'pulse' when it is shortly preceded by a weak 'prepulse' stimulus. The nucleus accumbens plays a pivotal role in the regulation of prepulse inhibition in rats, but the
Neumann KR, Feldon J, Yee BK, Pothuizen HH   +3 more
core   +1 more source

Inhibitory effects of prepulse stimuli on the electrophysiological responses to startle stimuli in the deep layers of the superior colliculus

Frontiers in Neuroscience
BackgroundPrepulse inhibition (PPI) is a phenomenon where a weak prepulse stimulus inhibits the startle reflex to a subsequent stronger stimulus, which can be induced by various sensory stimulus modalities such as visual, tactile, and auditory stimuli ...
Yu Ding, Yu Ding, Huan Jiang, Na Xu, Na Xu, Liang Li   +5 more
doaj   +1 more source

Early maternal deprivation and prepulse inhibition: the role of the postdeprivation environment.

, 2002
Early postnatal maternal deprivation leads to a variety of biochemical and behavioural alterations in the offspring, some of which do not develop until adulthood, like deficits in prepulse inhibition.
Cools, A.R., Ellenbroek, A.A.
core   +1 more source

Effects of Metabolic Dysfunction–Associated Steatohepatitis in Alertness, Associative Learning, and Astrocyte Density

Brain and Behavior
Purpose Metabolic dysfunction–associated steatohepatitis (MASH) is a prevalent disease caused by high fat and high cholesterol intake, which leads to systemic deterioration. The aim of this research is to conduct a psychobiological exploration of MASH in
Sara G. Higarza, Marina De Antón‐Cosío, Candela Zorzo, Jorge L. Arias, Natalia Arias   +4 more
doaj   +1 more source

Prepulse inhibition of the blink reflex is abnormal in functional movement disorders. [PDF]

, 2019
BACKGROUND: Patients with functional movement disorders also typically have functional somatic symptoms, including pain, fatigue, and sensory disturbance.
Edwards, MJ, Anna Fečíková, David Kemlink, Tereza Serranová, Zuzana Hanzlíková, Evžen Růžička, Matěj Slovák, Tomáš Sieger, Valls-Solé, J, Kemlink, D, Fečíková, A, Markus Kofler, Serranová, T, Josep Valls‐Solé, Kofler, M, Sieger, T, Gabriela Věchetová, Slovák, M, Věchetová, G, Růžička, E, Mark J. Edwards, Hanzlíková, Z   +21 more
core   +1 more source

Minocycline and risperidone prevent microglia activation and rescue behavioral deficits induced by neonatal intrahippocampal injection of lipopolysaccharide in rats.

PLoS ONE, 2014
BackgroundVarious signs of activation of microglia have been reported in schizophrenia, and it is hypothesized that microglia activation is closely associated with the neuropathology of schizophrenia.MethodsNeonatal intrahippocampal injection of ...
Furong Zhu, Yingjun Zheng, Yu-qiang Ding, Yong Liu, Xianghui Zhang, Renrong Wu, Xiaofeng Guo, Jingping Zhao   +7 more
doaj   +1 more source

Sex differences in prepulse inhibition deficits in chronic schizophrenia

, 2004
Recent years have seen a dramatic growth in the number of studies using prepulse inhibition (PPI) paradigms to index information processing deficits in schizophrenia.
Aasen, I, Kumari, V, Tonmoy Sharma, Ingrid Aasen, Sharma, T, Veena Kumari   +5 more
core   +1 more source

Prepulse inhibition of the startle response in men with schizophrenia - Effects of age of onset of illness, symptoms, and medication

, 2000
Background: Prepulse inhibition of the startle reflex response refers to the ability of a weak prestimulus to transiently inhibit the response to a closely following strong sensory stimulus.
Soni, W, Kumari, V, Mathew, V M, Sharma, T   +3 more
core   +1 more source

GAT1 KO mice show impaired prepulse inhibition and latent inhibition.

, 2013
A1, Startle amplitude to a 120 dB acoustic stimulus was normal in GAT1 KO mice. A2, GAT1 KO mice exhibited significantly reduced percent prepulse inhibition of the acoustic startle response across prepulse intensities (70, 75, 80 dB).
Jian Fei (95896), Tian-Le Xu (262261), Zhe Yu (44694), Hui Cao (182176), Zhong Chen (32985), Yi-Zhi Wang (438881), Gang Hu (132827), Neng Gong (270305), Qi Fang (199280), Xian Xiao (438880), You-Qing Cai (438882)   +10 more
core   +1 more source

A Cellular Mechanism for Prepulse Inhibition [PDF]

, 2003
In prepulse inhibition (PPI), startle responses to sudden, unexpected stimuli are markedly attenuated if immediately preceded by a weak stimulus of almost any modality.
Tian, Li-Ming, Frost, William N, Mongeluzi, Donna L, Hoppe, Travis A, Li-Ming Tian, Jean Wang, William N Frost, Travis A Hoppe, Wang, Jean, Donna L Mongeluzi   +9 more
core   +1 more source