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Lancet, The, 2005 The inevitable deterioration in hearing ability that occurs with age--presbycusis--is a multifactorial process that can vary in severity from mild to substantial. Left untreated, presbycusis of a moderate or greater degree affects communication and can contribute to isolation, depression, and, possibly, dementia. These psychological effects are largely
George A, Gates, John H, Mills
exaly +5 more sources
NeuroImage, 2023 Recent studies suggest that the interaction between presbycusis and cognitive impairment may be partially explained by the cognitive-ear link. However, the underlying neurophysiological mechanisms remain largely unknown.
Fuxin Ren, Zongrui Dai, Steve C N Hui
exaly +3 more sources
Novel insights into mechanisms and therapeutics for presbycusis [PDF]
HeliyonPresbycusis, also referred to as age-related hearing loss, poses a substantial burden on both individuals and society. The hallmark of presbycusis is a progressive decrease in auditory sensitivity.
Xiaoying Lin +3 more
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Mechanisms of Sensorineural Cell Damage, Death and Survival in the Cochlea [PDF]
Frontiers in Aging Neuroscience, 2015 The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well
Allen Frederic Ryan +4 more
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Presbycusis Disrupts Spontaneous Activity Revealed by Resting-State Functional MRI
Frontiers in Behavioral Neuroscience, 2018 Purpose: Presbycusis, age-related hearing loss, is believed to involve neural changes in the central nervous system, which is associated with an increased risk of cognitive impairment.
Yu-Chen Chen +2 more
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Biomarkers of Presbycusis and Tinnitus in a Portuguese Older Population [PDF]
Frontiers in Aging Neuroscience, 2017 Introduction: Presbycusis or age-related hearing loss (ARHL) is a ubiquitous health problem. It is estimated that it will affect up to 1.5 billion people by 2025. In addition, tinnitus occurs in a large majority of cases with presbycusis.
Haúla F. Haider +10 more
doaj +3 more sources
A genome-wide association study about presbycusis and brain cortical structure: Neuroimaging traits from a Mendelian randomization study [PDF]
Journal of OtologyObjectives The causal association between presbycusis and changes in cerebral cortex structure was evaluated through Mendelian randomization (MR).Methods Presbycusis data, serving as the exposure trait, was analyzed using data from the ninth release of ...
Zhencheng Gao +3 more
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Transcriptomic analysis reveals the function of m6A regulators in aged cochlea [PDF]
Brazilian Journal of OtorhinolaryngologyObjective: Presbycusis is a prevalent health issue among the elderly. Previous studies have shown mechanisms related to this condition, but the underlying mechanisms of presbycusis remain elusive.
Yanbing Lai +6 more
doaj +2 more sources
Frontiers in Neuroscience, 2018 The incidences of presbycusis and dementia are high among geriatric diseases. Presbycusis is the general term applied to age-related hearing loss and can be caused by many risk factors, such as noise exposure, smoking, medication, hypertension, family ...
Cui Fan, Yilai Shu, Mingliang Xiang
exaly +3 more sources
The Effect of Coenzyme Q10 on Tinnitus Severity and Sleep Quality in Patients with Presbycusis [PDF]
Iranian Journal of OtorhinolaryngologyIntroduction: Tinnitus is one of the symptoms of presbycusis that affects patients' sleep and social life. This study aimed to determine the effect of coenzyme Q10 (CoQ10) on treating tinnitus due to presbycusis.
Rohollah Abbasi +3 more
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