Results 91 to 100 of about 3,827,941 (337)

Integrated metabolomic and transcriptomic analysis of Pogostemon cablin shed new light on the complete biosynthesis pathway of pogostone

Frontiers in Plant Science
Pogostemon cablin (patchouli) is a well-known perennial herbaceous plant for traditional Chinese medicine, and its primary bioactive compounds are patchoulol and pogostone.
Sen Wang, Zhaoqi Zeng, Zhaoqi Zeng, Qi Zhang, Wenhua Liu, Qinjian Liu, Chong Xie, Chong Xie, Jinlong Bei, Bingxian Chen, Aixia Zhang   +10 more
doaj   +1 more source

A DNA Methylation-Based Panel for the Prognosis and Dagnosis of Patients With Breast Cancer and Its Mechanisms

Frontiers in Molecular Biosciences, 2020
ObjectiveTo identify DNA methylation related biomarkers in patients with breast cancer (BC).Materials and MethodsA total of seven BC methylation studies including 1,438 BC patients or breast tissues were included in this study. An elastic net regularized
Xiao-Ping Liu, Jinxuan Hou, Chen Chen, Chen Chen, Li Guan, Li Guan, Han-Kun Hu, Sheng Li, Sheng Li   +8 more
doaj   +1 more source

Actively decaying or just poorly preserved? Can we tell when plant and invertebrate remains in urban archaeological deposits decayed? [PDF]

, 2004
We have recendy argued that poorly preserved delicate macrofossil remains of plants and invertebrates in near-surface deposits in York are in active decay, rather than being preserved in stasis, part-way down the decay trajectory.
Hall, A., Kenward, H.
core  

Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications

Molecules, 2019
Piper species are aromatic plants used as spices in the kitchen, but their secondary metabolites have also shown biological effects on human health. These plants are rich in essential oils, which can be found in their fruits, seeds, leaves, branches ...
B. Salehi, Z. Zakaria, R. Gyawali, S. Ibrahim, J. Rajković, Z. Shinwari, T. Khan, Javad Sharifi‐Rad, Adem Ozleyen, Elif Turkdonmez, Marco Valussi, T. Tumer, Lianet Monzote Fidalgo, M. Martorell, W. Setzer   +14 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Optimization of the bi-oleothermal treatment process for wood preservation and fireproofing [PDF]

, 2011
The bi-oleothermal© process (combination of oil and heat treatment) is a well mastered alternative method for wood protection. However, the fire behavior and resistance to decay of bi-oleothermally treated wood are not good enough to ensure performance ...
Alfos, Carine, Céron, Mathieu, Goyer, Morgan, Kutnik, Magdalena, Simon, Frédéric, Thévenon, Marie-France   +5 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Notes on Contraction Theory

, 2005
These notes derive a number of technical results on nonlinear contraction theory, a comparatively recent tool for system stability analysis. In particular, they provide new results on the preservation of contraction through system combinations, a ...
Slotine, Jean-Jacques, Tabareau, Nicolas
core   +3 more sources

Understanding the Effects of Lactose Hydrolysis Modeling on the Main Oligosaccharides in Goat Milk Whey Permeate. [PDF]

, 2019
Enzymatic hydrolysis of lactose is a crucial step to improve the efficiency and selectivity of membrane-based separations toward the recovery of milk oligosaccharides free from simple sugars.
Barile, Daniela, C McNabb, Warren, C Roy, Nicole, Maria Leite Nobrega de Moura Bell, Juliana, Thum, Caroline, Weinborn, Valerie   +5 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source