Results 141 to 150 of about 3,722,975 (358)

Retention of Mercurial Preservatives in Desiccated Biological Products [PDF]

Journal of Clinical Microbiology, 1975
A variety of bacterins, vaccines, and antisera retained greater than 90% of their original level of mercurial preservative after lyophilization, and this might influence certain uses of these products.
openaire   +3 more sources

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

Molecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns, Ulrik Ringborg, Julio Celis, Bengt Jönsson, Michael Baumann   +4 more
wiley   +1 more source

Production and preservation of resins – past and present

Biological Reviews of The Cambridge Philosophical Society, 2018
Amber is fossilised plant resin. It can be used to provide insights into the terrestrial conditions at the time the original resin was exuded. Amber research thus can inform many aspects of palaeontology, from the recovery and description of enclosed ...
L. Seyfullah, C. Beimforde, Jacopo Dal Corso, V. Perrichot, J. Rikkinen, A. Schmidt   +5 more
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Tissue- and Species-Specific Patterns of RNA metabolism in Post-Mortem Mammalian Retina and Retinal Pigment Epithelium. [PDF]

, 2019
Accurate analysis of gene expression in human tissues using RNA sequencing is dependent on the quality of source material. One major source of variation in mRNA quality is post-mortem time.
Blackshaw, Seth, Kallestad, Les, Khalil, Ahmad M, Palczewski, Krzysztof   +3 more
core  

A discrete optimization model for preserving biological diversity

Applied Mathematical Modelling, 1995
In this paper we propose an operational framework within which the concept of diversity is measurable. Based on an interspecies dissimilarity index, we develop a series of progressively more efficient integer programming formulations with the objective of maximizing biological diversity under resource constraints.
Krishna S. Dhir, Fred Glover, Kuo Ching-Chung   +2 more
openaire   +2 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Assembly and analysis of the complete mitochondrial genome of Leonurus japonicus (Lamiaceae)

Scientific Reports
Leonurus japonicus Houtt. (L. japonicus), as an important plant resource with both ornamental and medicinal value, has now spread worldwide and is widely studied.
Qun Hu, Qing Li, Yin Mao, Yongjian Luo, Zhijun Deng, Wenhu Zhang   +5 more
doaj   +1 more source

Maximum Bound Principle and Bound Preserving ETD schemes for a Phase-Field Model of Tumor Growth with Extracellular Matrix Degradation [PDF]

arXiv
In cancer research, the role of the extracellular matrix (ECM) and its associated matrix-degrading enzyme (MDE) has been a significant area of focus. This study presents a numerical algorithm designed to simulate a previously established tumor model that incorporates various biological factors, including tumor cells, viable cells, necrotic cells, and ...
arxiv