Results 151 to 160 of about 2,788,343 (358)

Rethinking authenticity in digital art preservation [PDF]

open access: yes, 2012
In this paper I am discussing the repositioning of traditional conservation concepts of historicity, authenticity and versioning in relation to born digital artworks, upon findings from my research on preservation of computer-based artifacts ...
Innocenti, P.
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Plenty of Bark, But Not Much Bite: Putting Teeth Back into Historic Preservation Enforcement in D.C. [PDF]

open access: yes, 2007
Washington, D.C. has one of the largest inventories of protected historic buildings of any city in the United States. Over 25,000 structures stand within the city\u27s borders that are either individually landmarked or contributing buildings within a ...
Sale, Winston
core   +1 more source

Improved Deep Embedded Clustering with Local Structure Preservation

open access: yesInternational Joint Conference on Artificial Intelligence, 2017
Xifeng Guo   +3 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Preservation of panorama mesdag, the Haque [PDF]

open access: yes, 2012
This paper deals with the preservation of the Panorama Mesdag, a cylindrical painting, more than 14 meters high and 120 meters in circumference. The vista of the sea, the dunes and Scheveningen village was painted by one of the most famous painters of ...
Koning, M. de, Stoel, A.E.C. van der
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Advanced imaging strategies in cardiac organoids: bridging the gap between structural complexity and functional analysis

open access: yesCardiovascular Diabetology
Cardiac organoids have emerged as pivotal models for cardiovascular disease research and drug development due to their ability to recapitulate the in vivo cardiac microenvironment, structure, and function.
Keyan Zhao   +9 more
doaj   +1 more source

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