Results 141 to 150 of about 2,788,343 (358)
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Frontiers in PhysiologyBackgroundThis systematic review and meta-analysis aims to investigate the effects of virtual reality (VR) exercise compared to traditional rehabilitation on pain, function, and muscle strength in patients with knee osteoarthritis (KOA).
Wei Wei +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
House of the Setting Sun: New Orleans, Katrina, and The Role of Historic Preservation Laws in Emergency Circumstances [PDF]
, 2006 In the aftermath of Hurricane Katrina, while various government bodies scrambled to address the myriad tragedies and emergencies that arose from the disaster, one critical question went largely unanswered and ignored: What was to become of the historic ...
Christoff, Annie
core +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Presenting Pompeii: Reconciling Relationships between Configuration and Conservation [PDF]
, 2013 Mark Twain’s idealized testimonial in his travelogue Innocents Abroad is not a revolutionary phenomenon. Pompeii has long been considered a city with breathtaking preservation, but the extent of preservation has been a recent source of controversy.
Sheldon, Karilyn
core +2 more sources
Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer.
New England Journal of Medicine, 2003 A. Forastiere +14 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source