Results 131 to 140 of about 2,788,343 (358)

Status Report of the DPHEP Study Group: Towards a Global Effort for Sustainable Data Preservation in High Energy Physics

open access: yes, 2012
Data from high-energy physics (HEP) experiments are collected with significant financial and human effort and are mostly unique. An inter-experimental study group on HEP data preservation and long-term analysis was convened as a panel of the ...
Akopov, Z.   +89 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Enzymatic Characterization of SpPAL Genes in S. polyrhiza and Overexpression of the SpPAL3

open access: yesPlants
Phenylalanine ammonia-lyase (PAL, EC 4.3.1.5) catalyzes the deamination of phenylalanine, which is the initial step in the biosynthesis of phenylpropanoids.
Xiaoxue Li   +11 more
doaj   +1 more source

Sound Recognition of Historical Visibility: The Radio Preservation Task Force of the Library of Congress: Introduction [PDF]

open access: yes, 2016
This issue of Journal of Radio & Audio Media serves as a gesture toward increasing attention to many untold cultural sound histories. The “question” of radio preservation, we’re just coming to realize, closely equates to our responsibility to identify ...
Keeler, Amanda R   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Project Summary: Preservation Plan for Warren, RI [PDF]

open access: yes, 2011
This document summarizes the project that created a historical preservation plan for the Town of Warren, RI by the students in Professor Arnold Robinson’s graduate-level course: Historical Preservation ...
Community Partnerships Center, Roger Williams University
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure

open access: yesFrontiers in Medicine
BackgroundCurrent therapeutic approaches for premature ovarian failure (POF) are often inadequate in clinical practice and some raise ethical concerns.
Guojie Ji   +9 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

An analysis of the phonological system of Dayak Bentian language in East Kalimantan, Indonesia

open access: yesCogent Arts & Humanities
This research discusses the phonological description of the Dayak Bentian (DB) language, its comparison with other Dayak languages, and its relation to Austronesian language patterns, as part of language documentation.
Andi Indah Yulianti   +5 more
doaj   +1 more source

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