Results 131 to 140 of about 1,511,062 (337)

Family Preservation Research: Where We\u27ve Been, Where We Should Be Going [PDF]

, 2001
Although the literature has provided many critiques of research done on family preservation programs, these critiques have usually been limited to the studies \u27 assumptions, approach, or methodology.
Meezan, William, Yoo, Jane
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The preservation and sustainability of research data [PDF]

, 2007
This talk is based in part on a survey carried out for APSR and APAC in 2006, which led to the AERES report (http://www.apsr.edu.au/publications/projects.htm) The survey looked at the issues surrounding the management and preservation of a large range of
Australian Partnership for Sustainable Repositories (APSR)
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Development of a Methodology to Understand Climate-induced Damage in Decorated Oak Wood Panels [PDF]

, 2017
Climate-induced damage in decorated oak wood panels is considered to be a high risk for pre-eminent museum collections. To advise museums on the development of sustainable future preservation strategies and rational guidelines for indoor climate ...
Ankersmit, H.A., Ekelund, S.E., Gauvin, C.A.F., Groves, R.M., Jorissen, A.J.M., Luimes, R.A, Schellen, H.L., Suiker, A.S.J., Van Duin, P.H.J.C.   +8 more
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Literacy Preservation and Transmission of Youyang Chinese Folk Songs

International Journal of Education and Literacy Studies
Youyang folk songs represent a significant component of China’s intangible cultural heritage from Youyang County in Chongqing Municipality, China. The study objective is to analyze the education literacy in preserving and transmitting Youyang Chinese ...
Can Fan, Sayam Chuangprakhon, Linyan Li
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Efficient Privacy-Preserving Range Query With Leakage Suppressed for Encrypted Data in Cloud-Based Internet of Things

IEEE Access
Data owners are increasingly drawn to outsource their data due to the massive processing capabilities and scalable storage offered by cloud-based Internet of Things (IoT) solutions.
Sultan Basudan, Abdulrahman Alamer
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source