Results 241 to 250 of about 433,325 (294)

The impact of CSF gusher on preservation of low frequency residual hearing following cochlear implantation. [PDF]

Pak J Med Sci
Fatima G, Jabeen R, Ahmad J, Jahangeer Badar M, Shahzad J, Saqulain G.   +5 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Evaluation of the Effectiveness of the Socket Preservation Technique Using Allogeneic and Xenogeneic Materials: A Randomized Controlled Trial. [PDF]

J Funct Biomater
Wróbel P, Jędzierowska M, Piecuch A, Bąk M, Adamczyk J, Pławecki P, Mojżesz P, Wachol K, Wójcik S, Starosta M, Cholewka A, Morawiec T.   +11 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Organ-sparing management of luminal gastrointestinal cancers: current and emerging approaches. [PDF]

Intern Med J
Van Stiphout CM, Miller A, Shepherdson M, Sammour T, Vatandoust S, Price T, Bright T, Defontgalland D, Karapetis CS, Roy AC.   +9 more
europepmc   +1 more source

Preserving Gadolinium Speciation in Environmental Waters: Establishing Hold Times and Storage Protocols for Reliable Analysis. [PDF]

ACS ES T Water
Ezzaldine A, Kanaththage M, Rubasinghege G, Frey B, Escobar GP, Coyte R.   +5 more
europepmc   +1 more source

Time to chemotherapy and oncofertility counseling in pediatric hematology/oncology patients: a single-center retrospective review. [PDF]

Front Oncol
Mariano J, Flanagan HB, Seymour KH, SanGiacomo N, Ogbutor N, Niknafs A, Hodges B, Evans A, Baran A, Andolina JR.   +9 more
europepmc   +1 more source

Breast Cancer and Ovarian Tissue Cryopreservation: SWOT Analysis. [PDF]

J Clin Med
Raimondo D, Doglioli M, Forastiere C, Vicenti R, Schirripa M, Pazzaglia E, Miscia M, Neola D, Bertoldo L, Massucci M, Serra M, Cobellis L, Seracchioli R, Raffone A.   +13 more
europepmc   +1 more source

Knowledge preservation in the era of big science and AI: strategies for sustainable scientific research. [PDF]

Nat Commun
Rainford PF, Occhipinti A, Wang B, Stepney S, Angione C, Verma S, Marucci L, Sharma K, Harris SA, Füchslin RM, Klipp E, Grierson CS, Weyland MS, Mogre A, Fellermann H, Doan LMT, Gherman IM, Pyne ALB, Rudge TJ, Berrelleza VMV, Gorochowski TE.   +20 more
europepmc   +1 more source