Results 61 to 70 of about 171,070,652 (247)

Technology of Data: Collection, Communication, Access and Preservation - IASSIST 2008

open access: yesIASSIST Quarterly, 2008
Technology of Data: Collection, Communication, Access and Preservation - IASSIST ...
Editors
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

ERPANET OAIS Training Report

open access: yes, 2003
The training seminar provided accessible and transferable training to participants on the OAIS model itself, its functionalities, and its wider potential applications. Participants gained familiarity with the main features of the model, and examined some

core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Principles for Digital Preservation

open access: yes, 2004
Published difficulties with long-term digital preservation prove to be largely confusions with language. Similar difficulties were addressed in early twentieth-century philosophy.
Gladney, Dr. H.M.
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

BlogForever D3.1: Preservation Strategy [PDF]

open access: yes, 2013
This report describes preservation planning approaches and strategies recommended by the BlogForever project as a core component of a weblog repository design.
Arango-Docio   +9 more
core   +1 more source

Tools for quantitative comparison of preservation strategies

open access: yes, 2012
This report describes the tools developed by IT Innovation for quantitative comparison of preservation strategies. The tools have been open sourced and are publicly available on a website which includes documentation and features for bug reporting and ...
Addis, Matthew   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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