Results 121 to 130 of about 93,754 (299)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Forty-hour preservation of the rabbit heart: Optimal osmolarity, [Mg2+], and pH of a modified UW solution

, 1994
James C. Stringham, Karen L. Paulsen, James H. Southard, Robert M. Mentzer, Folkert O. Belzer   +4 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Therapeutic Potential of Selenium as a Component of Preservation Solutions for Kidney Transplantation. [PDF]

Molecules, 2020
Ostróżka-Cieślik A, Dolińska B, Ryszka F.   +2 more
europepmc   +1 more source

Effectiveness Assessment of a Modified Preservation Solution Containing Thyrotropin or Follitropin Based on Biochemical Analysis in Perfundates and Homogenates of Isolated Porcine Kidneys after Static Cold Storage [PDF]

, 2021
Aneta Ostróżka-Cieślik, Barbara Dolińska, Florian Ryszka   +2 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Study on the Antibacterial Efficacy of Ceftazidime-Avibactam Combined with Aztreonam against Multidrug-Resistant Bacteria in Hypothermic Organ Preservation Solution [PDF]

Yan Duan, Daqian Tang, Yuhong Li, Pei Zhang, Yuxiang Wan, Kang Wu, Yanfeng Li, Junhao Yu, Wenyu Zhao, Yanhua Li, Mingxing Sui, Li Zeng   +11 more
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Flexible preservation and access solutions

, 2016
Matthew Addis
openalex   +1 more source

Commentary: Long-term solutions to revive eye banking in India in COVID-19 era - Needs more than long-term corneal preservation

, 2020
SamarK Basak, Basak Soham
openalex   +1 more source