Results 131 to 140 of about 427,464 (325)

Dexmedetomidine suppresses glucose‐stimulated insulin secretion in pancreatic β‐cells

FEBS Open Bio, Volume 15, Issue 4, Page 634-646, April 2025.
Dexmedetomidine decreases insulin release and affects glucose metabolism; however, the specific mechanism remains largely unknown. This study shows clinically relevant doses of dexmedetomidine suppressed glucose‐stimulated insulin secretion. There was no significant difference in oxygen consumption rate, intracellular ATP levels, or caspase‐3/7 ...
Munenori Kusunoki, Kiichi Hirota, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Mikio Hayashi   +5 more
wiley   +1 more source

24-HOUR RAT LIVER PRESERVATION USING UW SOLUTION AND SOME SIMPLIFIED VARIANTS

, 1989
R Sumimoto, Neville V. Jamieson, Kenjiro Wake, Naoshi Kamada   +3 more
openalex   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, Volume 15, Issue 5, Page 773-792, May 2025.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

On sequences preserving summability [PDF]

arXiv
In this paper, we study sequences of positive numbers preserving summability. In particular, the open set property for such a family of sequences is shown. Several classes of sequences preserving summability, including polynomials, sums of powers, and solutions of some difference equations, are introduced.
arxiv  

Therapeutic Potential of Selenium as a Component of Preservation Solutions for Kidney Transplantation. [PDF]

Molecules, 2020
Ostróżka-Cieślik A, Dolińska B, Ryszka F.   +2 more
europepmc   +1 more source

Three solutions for preservation of the rabbit heart at 0° C

, 1988
T A English, Dereck Wheeldon, J. Foreman, David G. Gadian, D.E. Pegg, Steven Williams   +5 more
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

On measure-preserving selection of solutions of ODEs

For every $k \in \mathbb{N}$ and $α\in (0,1)$ we construct a divergence-free $u \in C^k([0,T],C^α(\mathbb{T}^d,\mathbb{R}^d))$, $d \geq 2$, such that there is no measurable selection of solutions of the ODE $\dot{X}_t = u(t,X_t)$ that preserves the Lebesgue measure.
openaire   +3 more sources

A Comparison of Solutions for Lung Preservation Using Pulmonary Alveolar Type II Cell Viability

, 1988
M Hachida, Dave S.�B. Hoon, Donald L. Morton   +2 more
openalex   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, Volume 15, Issue 5, Page 822-835, May 2025.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source