Results 41 to 50 of about 427,464 (325)

Application of Coating Chitosan Derivatives (N,O–Carboxymethyl Chitosan/Chitosan Oligomer Saccharide) in Combination with Polyvinyl Alcohol Solutions to Preserve Fresh Ngoc Linh Ginseng Quality

open access: yesFoods, 2023
The postharvest preservation of Ngoc Linh ginseng (NL ginseng) is essential to retain its quality and sensory values for prolonged storage. In this study, the efficacy of NL ginseng preservation by coating chitosan derivatives in combination with ...
Ngoc Nguyen   +10 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

The preservation of ophthalmic solutions with antibacterial combinations

open access: yesJournal of Pharmacy and Pharmacology, 1971
Abstract Solutions of pilocarpine, atropine and physostigmine preserved with benzalkonium, chlorhexidine, phenylmercuric nitrate (PMN), chlorocresol and chlorbutol in simple solution and in combination with either phenylethanol or disodium edetate (EDTA), were contaminated on two separate occasions with high inocula of P.
R. M. E. Richards, R. J. Mcbride
openaire   +4 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Human colon organoid differentiation from induced pluripotent stem cells using an improved method

open access: yesFEBS Letters, Volume 599, Issue 6, Page 912-924, March 2025.
We compared established protocols to differentiate induced pluripotent stem cells into colon organoids and found that activation of bone morphogenetic protein 2 signaling induced gene expression of colon‐specific markers. Adenovirus‐mediated transduction of the transcription factors HOXD13 or SATB2 further enhanced colonic gene expression, suggesting ...
I‐Ting Lee   +4 more
wiley   +1 more source

Effect of cold preservation/reperfusion on glycogen content of liver. Concise review

open access: yesAnnals of Hepatology, 2005
Livers cold preserved during variable periods of ischemia suffer functional, morphological and hemodynamic alteration, which are exacerbated when they are reperfused. One important injury is glycogen depletion during cold ischemia/ reperfusion. How liver
Alejandra B. Quintana   +2 more
doaj  

A classification of volume preserving generating forms in R^3 [PDF]

open access: yesDiscrete and Continuous Dynamical Systems - Series A 36.4, pp. 2285-2303 (2016), 2014
In earlier work, Lomeli and Meiss used a generalization of the symplectic approach to study volume preserving generating differential forms. In particular, for the $\mathbb{R}^3$ case, the first to differ from the symplectic case, they derived thirty-six one-forms that generate exact volume preserving maps.
arxiv   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1055-1074, April 2025.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Residues R177 and S178 of the human Na+/H+ antiporter NHA2 are involved in its inhibition by the flavonoid phloretin

open access: yesFEBS Letters, Volume 599, Issue 6, Page 901-911, March 2025.
The human Na+/H+ antiporter NHA2 transports Na+ or Li+ in exchange for protons across cell membranes, and its dysfunction results in various pathologies, e.g., fertility disorders, hypertension, or diabetes. This work provides the molecular characterization of interactions of NHA2 with its specific inhibitor phloretin, which can be helpful for the ...
Olga Zimmermannova   +3 more
wiley   +1 more source

Molecular insights into the modulation of the 5HT2A receptor by serotonin, psilocin, and the G protein subunit Gqα

open access: yesFEBS Letters, Volume 599, Issue 6, Page 876-891, March 2025.
We explore 5HT2A receptor activation, a key target for psychedelic drugs, using molecular dynamics simulations. Without Gqα, the active receptor collapses to an inactive conformation, underscoring the G‐protein's role. Discovery of an intermediate “partially‐open” state and the higher affinity of ligands to the orthosteric binding site provides ...
Niklas Viohl   +2 more
wiley   +1 more source

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