Results 61 to 70 of about 427,464 (325)

Volume-preserving exponential integrators [PDF]

open access: yesarXiv, 2018
As is known that various dynamical systems including all Hamiltonian systems preserve volume in phase space. This qualitative geometrical property of the analytical solution should be respected in the sense of Geometric Integration. This paper analyses the volume-preserving property of exponential integrators in different vector fields.
arxiv  

Preservation of log-Hölder coefficients of the vorticity in the transport equation [PDF]

open access: yesarXiv, 2021
We show that the log-H\"{o}lder coefficients of a solution to the transport equation is preserved in time.
arxiv  

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Fluid preservation in brain banking: a review

open access: yesFree Neuropathology
Fluid preservation is nearly universally used in brain banking to store fixed tissue specimens for future research applications. However, the effects of long-term immersion on neural circuitry and biomolecules are not well characterized.
Andrew McKenzie   +5 more
doaj   +1 more source

Bound-preserving discontinuous Galerkin methods with modified Patankar time integrations for chemical reacting flows [PDF]

open access: yesarXiv, 2022
In this paper, we develop bound-preserving discontinuous Galerkin (DG) methods for chemical reactive flows. There are several difficulties in constructing suitable numerical schemes. First of all, the density and internal energy are positive, and the mass fraction of each species is between 0 and 1.
arxiv  

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

Energy-preserving continuous-stage Runge-Kutta-Nyström methods [PDF]

open access: yesarXiv, 2018
Many practical problems can be described by second-order system $\ddot{q}=-M\nabla U(q)$, in which people give special emphasis to some invariants with explicit physical meaning, such as energy, momentum, angular momentum, etc. However, conventional numerical integrators for such systems will fail to preserve any of these quantities which may lead to ...
arxiv  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Ethanol fuel improves arthropod capture in pitfall traps and preserves DNA

open access: yesZooKeys, 2012
We tested the value of ethanol fuel as a killing solution in terms of sampling efficiency (species richness and accumulated abundance) and DNA preservation of Ensifera ground-dwelling specimens.
Neucir Szinwelski   +4 more
doaj   +1 more source

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