Results 61 to 70 of about 427,464 (325)
Volume-preserving exponential integrators [PDF]
As is known that various dynamical systems including all Hamiltonian systems preserve volume in phase space. This qualitative geometrical property of the analytical solution should be respected in the sense of Geometric Integration. This paper analyses the volume-preserving property of exponential integrators in different vector fields.
arxiv
Preservation of log-Hölder coefficients of the vorticity in the transport equation [PDF]
We show that the log-H\"{o}lder coefficients of a solution to the transport equation is preserved in time.
arxiv
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek+15 more
wiley +1 more source
Fluid preservation in brain banking: a review
Fluid preservation is nearly universally used in brain banking to store fixed tissue specimens for future research applications. However, the effects of long-term immersion on neural circuitry and biomolecules are not well characterized.
Andrew McKenzie+5 more
doaj +1 more source
Bound-preserving discontinuous Galerkin methods with modified Patankar time integrations for chemical reacting flows [PDF]
In this paper, we develop bound-preserving discontinuous Galerkin (DG) methods for chemical reactive flows. There are several difficulties in constructing suitable numerical schemes. First of all, the density and internal energy are positive, and the mass fraction of each species is between 0 and 1.
arxiv
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon+5 more
wiley +1 more source
Energy-preserving continuous-stage Runge-Kutta-Nyström methods [PDF]
Many practical problems can be described by second-order system $\ddot{q}=-M\nabla U(q)$, in which people give special emphasis to some invariants with explicit physical meaning, such as energy, momentum, angular momentum, etc. However, conventional numerical integrators for such systems will fail to preserve any of these quantities which may lead to ...
arxiv
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Ethanol fuel improves arthropod capture in pitfall traps and preserves DNA
We tested the value of ethanol fuel as a killing solution in terms of sampling efficiency (species richness and accumulated abundance) and DNA preservation of Ensifera ground-dwelling specimens.
Neucir Szinwelski+4 more
doaj +1 more source