Results 71 to 80 of about 93,754 (299)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Digital preservation practices in academic libraries in South Africa in the wake of the digital revolution

South African Journal of Information Management, 2019
Background: The preservation of digital resources in academic institutions in South Africa is an imperative because of the proliferation of digital resources and the realities of the digital revolution. The study focused on digital preservation practices
Tlou M. Masenya, Patrick Ngulube
doaj   +1 more source

A modified CZ-1 preserving solution for organ transplantation: comparative study with UW preserving solution

Chinese Medical Journal, 2008
The University of Wisconsin colloid based preserving solution (UW solution) is the most efficient preserving solution for multiorgan transplantation. Unfortunately, unavailability of delayed organ preserving solutions hindered further progression of cardinal organ transplantation in China.
Jun-hua, Zheng, Zhi-lian, Min, Yu-li, Li, You-hua, Zhu, Ting-jun, Ye, Jian-qiu, Li, Tie-wen, Pan, Guo-shan, Ding, Meng-long, Wang   +8 more
openaire   +2 more sources

The Role of IGL-2 Preservation Solution on Rat Livers during SCS and HOPE [PDF]

, 2022
Njikem Asong-Fontem, Arnau Panisello‐Roselló, Mylène Sebagh, Mathilde Gonin, Joan Roselló‐Catafau, René Adam   +5 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Preservation of Methane Hydrates Prepared from Dilute Electrolyte Solutions

International Journal of Chemical Engineering, 2009
The anomalous or self-preservation of methane hydrate at atmospheric pressure and temperatures below the ice point was investigated to determine whether this phenomenon might have applications in the storage and transportation of natural gas.
Hiroshi Sato, Takanori Tsuji, Tetsunari Nakamura, Koichi Uesugi, Takahiro Kinoshita, Masahiro Takahashi, Hiroko Mimachi, Toru Iwasaki, Kazunari Ohgaki   +8 more
doaj   +1 more source

Machine perfusion in clinical trials: the preservation solution bias [PDF]

, 2011
Nicolas Chatauret, Raphaël Thuillier, Benoı̂t Barrou, Thierry Hauet, Michel Eugène   +4 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

³¹P-NMR study of cardiac preservation: St. Thomas' Hospital cardioplegic solution versus UW preservation solution

Transplant International, 1991
Ex vivo cardiac preservation was evaluated by measuring the catabolism of high-energy phosphate (ATP and creatine phosphate, CrP) using 31P-NMR spectroscopy. After cardioplegic arrest St. Thomas' Hospital cardioplegic solution (group A), and University of Wisconsin (UW) preservation solution (group B) were tested.
Minten, J., Hecke, P., Vanstapel, F., Flameng, W.   +3 more
openaire   +2 more sources

Type of Preservation Solution, UW or HTK, Has an Impact on the Incidence of Biliary Stricture following Liver Transplantation: A Retrospective Study [PDF]

, 2019
Rojbin Karakoyun, Antonio Romano, Johan Nordström, Bo‐Göran Ericzon, Greg Nowak   +4 more
openalex   +1 more source