Results 81 to 90 of about 427,464 (325)
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić+31 more
wiley +1 more source
We assessed the associations between the gut microbiota and outcome in metastatic triple‐negative breast cancer patients treated with chemotherapy alone or chemotherapy in combination with immunotherapy. Our data indicate that high gut microbiota alpha diversity was associated with improved clinical outcome and with benefit from immunotherapy.
Andreas Ullern+8 more
wiley +1 more source
Volume preserving mean curvature flow for star-shaped sets [PDF]
We study the evolution of star-shaped sets in volume preserving mean curvature flow. Constructed by approximate minimizing movements, our solutions preserve a strong version of star-shapedness. We also show that the solutions converges to a ball as time goes to infinity. For asymptotic behavior of the solutions we use the gradient flow structure of the
arxiv
High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies+9 more
wiley +1 more source
Preservation of convexity of solutions to parabolic equations
AbstractIn the present paper we find necessary and sufficient conditions on the coefficients of a parabolic equation for convexity to be preserved. A parabolic equation is said to preserve convexity if given a convex initial condition, any solution of moderate growth remains a convex function of the spatial variables for each fixed time.
Johan Tysk, Svante Janson
openaire +2 more sources
Male infertility is a known risk factor for the development of testicular cancer. In this paper, we analyzed the expression profile of a microRNA panel by real‐time PCR and validated the results by digital PCR. Experimental and bioinformatics analyses allowed us to identify possible biomarkers able to discern men with a higher risk of developing ...
Carmen Ferrara+14 more
wiley +1 more source
Background: The preservation of digital resources in academic institutions in South Africa is an imperative because of the proliferation of digital resources and the realities of the digital revolution. The study focused on digital preservation practices
Tlou M. Masenya, Patrick Ngulube
doaj +1 more source
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
Preservation of Methane Hydrates Prepared from Dilute Electrolyte Solutions
The anomalous or self-preservation of methane hydrate at atmospheric pressure and temperatures below the ice point was investigated to determine whether this phenomenon might have applications in the storage and transportation of natural gas.
Hiroshi Sato+8 more
doaj +1 more source