Results 71 to 80 of about 195,517 (390)
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Risk Assessment of Triclosan, a Cosmetic Preservative
Triclosan (TCS) is an antimicrobial compound used in consumer products. The purpose of current study was to examine toxicology and risk assessment of TCS based on available data.
Jung Dae Lee+9 more
semanticscholar +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Glaucoma therapy: preservative-free for all?
Preservatives used in topical glaucoma medications have a plethora of well-described toxic effects on the ocular surface. Such ocular toxicity is manifest clinically as ocular surface disease (OSD) and has been confirmed in epidemiologic, prospective ...
J. Thygesen
semanticscholar +1 more source
Scientific Opinion on the safety and efficacy of formaldehyde as a feed hygiene substance in feed for pigs and poultry [PDF]
The additive formaldehyde is an aqueous solution of formaldehyde (34–38 % w/w by specification) and methanol (0.5–15.0 % v/v by specification), with a maximum concentration of formic acid of 0.05 %.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj +1 more source
Tannin-boron wood preservatives [PDF]
Tannin-boron wood preservatives are alternative products to replace water-borne formulations based on copper. Interesting results in protection against fungus (pycnoporus sanguineus) were achieved with formulations based of 20% tannin solutions ...
Pizzi, Antonio+3 more
core
Invertibility preserving maps preserve idempotents.
Let \({\mathcal B}\) be a unital norm-closed operator algebra on some complex Banach space such that \({\mathcal B}\) contains all of the finite-rank operators. The main result of the paper under review is that, if \({\mathcal A}\) is a unital Banach algebra and \(\varphi:{\mathcal A}\to{\mathcal B}\) is a unital surjective linear mapping which takes ...
Brešar, Matej, Šemrl, Peter
openaire +4 more sources
Classical indications for hip preserving surgery are: femoro-acetabular impingement (FAI) (intra- and extra-articular), hip dysplasia, slipped capital femoral epiphysis, residual deformities after Perthes disease, avascular necrosis of the femoral head.
Hanke, Markus S.+4 more
openaire +3 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
The additives under assessment are lactic acid and calcium lactate. In 2015, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) delivered an Opinion on the safety and efficacy of lactic acid and calcium lactate.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)+25 more
doaj +1 more source