Real-World Transition to a Preservative-Free Fixed Combination of Dorzolamide/Timolol: Impact on the Ocular Surface Microenvironment, Safety, Tolerability, and Efficacy. [PDF]
Sanseau A +8 more
europepmc +1 more source
Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim +16 more
wiley +1 more source
Methodologies for Improving Antioxidant Properties and Absorption: 1st Edition. [PDF]
Tofani D.
europepmc +1 more source
Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika +22 more
wiley +1 more source
Comparison of Preservatives for the Prevention of Microbial Spoilage of Apple Pomace During Storage. [PDF]
Harratt A +7 more
europepmc +1 more source
Learned Conformational Space and Pharmacophore Into Molecular Foundational Model
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang +8 more
wiley +1 more source
Harnessing Pelargonium Odoratissimum Extracts for Sustainable Ground Meat Preservation. [PDF]
Ben Hsouna A +8 more
europepmc +1 more source
ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song +12 more
wiley +1 more source
Systematic Review and Meta-Analysis of Quality Claims Associated with Fresh Pet Food: Evaluating Scientific Evidence for Additives, Ingredient Quality, and Effects of Processing in Pet Nutrition. [PDF]
Jobe MT, Downs KM.
europepmc +1 more source

