Results 101 to 110 of about 8,537 (290)

Machine Learning-Based Surrogate Model for Press Hardening Process of 22MnB5 Sheet Steel Simulation in Industry 4.0. [PDF]

Materials (Basel), 2022
Abio A, Bonada F, Pujante J, Grané M, Nievas N, Lange D, Pujol O.   +6 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Wear mechanisms in press hardening of boron steel : identification and laboratory study [PDF]

, 2015
Press hardening, also known as hot stamping, is a hot sheet metal forming technique which allows producing lightweight components with complex geometry and outstanding mechanical properties.
Pujante Agudo, Jaume
core   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Residual Stresses and the Microstructure of Modeled Laser-Hardened Railway Axle Seats under Fatigue

Metals
Railway wheels are usually attached to axles by press-fitting; therefore, the mechanical processes taking place during operation can result in failure, with fatal consequences for the axle seats. This manuscript describes the effect of laser hardening on
Jiří Čapek, Karel Trojan, Jan Kec, Nikolaj Ganev, Ivo Černý, Tomáš Mužík   +5 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Maximasi Kuat Tekan Beton

Jurnal Teknik Industri, 2012
Concrete mixing obtained from the fine aggregate and coarse aggregate is sand, stone broken by adding sufficient adhesive cement and water as supporting material for purposes of chemical reactions during the process of concrete hardening and treatment ...
Lukito Prasetyo
doaj   +1 more source

Tailor tempering and hot-spotting of press hardened boron steels

Computer Methods in Materials Science, 2014
Hot forming processes are becoming a successful solution when complex geometrical components with high mechanical properties are desired. In fact, automotive structural components with tensile strengths higher than 1500MPa are being nowadays industrially produced.
Lander Galdos, Eneko Saenz de Argandoña, Joseba Mendiguren, Nuria Herrero, Rafael Ortubay, Xabier Agirretxe, José Miguel Martín   +6 more
openaire   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source