Results 111 to 120 of about 131,444 (236)

An elastoplastic framework for granular materials becoming cohesive through mechanical densification. Part I - small strain formulation

open access: yes, 2010
Mechanical densification of granular bodies is a process in which a loose material becomes increasingly cohesive as the applied pressure increases. A constitutive description of this process faces the formidable problem that granular and dense materials ...
Ahzi   +56 more
core   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew   +11 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

A thermoviscoplastic model with damage for simultaneous hot/cold forging analysis [PDF]

open access: yes, 2013
A constitutive model is presented for simultaneous hot/cold forming processes of steels. The phenomenological material theory is based on an enhanced rheological model and accounts temperature dependently for nonlinear hardening, thermally activated ...
Bröcker, C., Matzenmiller, A.
core  

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

A material model for aluminium sheet forming at elevated temperatures [PDF]

open access: yes, 2001
In order to accurately simulate the deep drawing or stretching of aluminum sheet at elevated\ud temperatures, a model is required that incorporates the temperature and strain-rate dependency of the material.\ud In this paper two models are compared: a ...
Bolt, P.J.   +2 more
core   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

A Nonvolume Preserving Plasticity Theory with Applications to Powder Metallurgy [PDF]

open access: yes, 1983
A plasticity theory has been developed to predict the mechanical response of powder metals during hot isostatic pressing. The theory parameters were obtained through an experimental program consisting of hydrostatic pressure tests, uniaxial compression ...
Cassenti, B. N.
core   +1 more source

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

open access: yesArthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim   +18 more
wiley   +1 more source

Effect of Cr/Mn-enriched carbide on retained austenite in a novel coating-free press-hardened steel

open access: yesJournal of Materials Research and Technology
The incorporation of retained austenite (RA) into press-hardened steel (PHS) has garnered significant attention due to its ability to enhance plasticity through the utilization of transformation-induced plasticity (TRIP) effect.
Fengkun Lin   +3 more
doaj   +1 more source

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