Results 61 to 70 of about 131,444 (236)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Enhancement of strength-ductility trade-off in a 2000 MPa grade press-hardened steel via refined martensite with stable high-density cementite

open access: yesJournal of Materials Research and Technology, 2023
High-strength press-hardened steels (PHSs) are characterized by a martensite structure of high strength and adequate ductility. Strengthening PHSs with high C contents is usually accompanied by a loss of ductility and toughness. To overcome this inherent
Zhuo Cheng   +9 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A multidisciplinary approach to study precipitation kinetics and hardening in an Al-4Cu (wt. %) alloy

open access: yes, 2018
A multidisciplinary approach is presented to analyse the precipitation process in a model Al-Cu alloy. Although this topic has been extensively studied in the past, most of the investigations are focussed either on transmission electron microscopy or on ...
Bellón, B.   +5 more
core   +1 more source

Fluctuation phenomena in crystal plasticity - a continuum model [PDF]

open access: yes, 2005
On microscopic and mesoscopic scales, plastic flow of crystals is characterized by large intrinsic fluctuations. Deformation by crystallographic slip occurs in a sequence of intermittent bursts ('slip avalanches') with power-law size distribution. In the
Michael Zaiser   +4 more
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Warm Deep Drawing of Aluminium Sheet [PDF]

open access: yes, 2003
Aluminium sheet drawing processes can be improved by manipulating local flow behaviour\ud by means of elevated temperatures and temperature gradients in the tooling. Forming tests\ud showed that a substantial improvement is possible not only for 5xxx but
Bolt, P.J.   +2 more
core   +1 more source

Correlation between rearrangements and soft modes in polymer glasses during deformation and recovery

open access: yes, 2015
We explore the link between soft vibrational modes and local relaxation events in polymer glasses during physical aging, active deformation at constant strain rate, and subsequent recovery.
Rottler, Joerg, Smessaert, Anton
core   +1 more source

Designing Of Advanced And Original Austempering Processes Based On Thermal Science And Engineering Physics Approaches [PDF]

open access: yes, 2016
In the paper, a small concentration of inverse solubility polymers in water and other liquid media is recommended to eliminate film boiling by means of reducing initial heat flux density.
Kobasko, N. (Nikolai)
core   +2 more sources

Home - About - Disclaimer - Privacy