Results 61 to 70 of about 79,402 (264)

Pressure fluctuation–vortex interaction in an ultra-low specific-speed centrifugal pump

Journal of Low Frequency Noise, Vibration and Active Control, 2019
To provide a comprehensive understanding of the pressure fluctuation–vortex interaction in non-cavitation and cavitation flow, in this article, the unsteady flow in an ultra-low specific-speed centrifugal pump was investigated by numerical simulation ...
Cong Wang, Yongxue Zhang, Zhiwei Li, Ao Xu, Chang Xu, Zhicheng Shi   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Numerical Calculation of the Influence of Working Conditions and Rotational Speed on Pressure Pulsation of a Self‐Priming Pump

Energy Science & Engineering
To accurately determine the pressure fluctuation characteristics of a specific self‐priming pump, a full three‐dimensional computational model was established, including the S‐tube, impeller domain, volute domain, gas‐liquid separation chamber, front and
Hai‐Bing Jiang, Shao‐Han Zheng, Yu‐Liang Zhang, Liang‐Huai Tong, Jin‐Fu Li, He‐Chao Guo   +5 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Detecting Pressure Waves during Earthquakes in an In-Service Pipeline System for Agricultural Irrigation using Numerical Analysis

e-Journal of Nondestructive Testing
Seismic hydrodynamic pressure, which is burst water pressure fluctuation induced by earthquakes, is often observed in water pipelines. The earthquake damage includes detachment and damage to pneumatic valves in curved pipe sections, and we believe that ...
Taiki Hagiwara, Takashi Ohkubo, Kaori Hoshino   +2 more
doaj   +1 more source

Influences on Bottom Hole Pressure in Riserless Drilling under Platform Disturbance

Shiyou jixie, 2022
In order to solve the problem of bottom hole pressure fluctuation caused by drilling platform disturbance in riserless drilling,a mathematical model for platform-drill string coupling vibration and a model for bottom hole pressure fluctuation were ...
Zuo Kai, Niu Guifeng, Wang Chuan, Liu Jing   +3 more
doaj  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Numerical analysis of pressure fluctuation in a multiphase rotodynamic pump with air–water two-phase flow

Oil & Gas Science and Technology, 2019
Pressure fluctuation in single-phase pumps has been studied widely, while less attention has been paid to research on multiphase pumps that are commonly used in the petroleum chemical industry.
Zhang Wenwu, Yu Zhiyi, Li Yongjiang, Yang Jianxin, Ye Qing   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Design of Adaptive Negative Pressure Regulating System for Glass Solidification of HLLW by Cold Crucible

Yuanzineng kexue jishu, 2022
During the operation of twostep cold crucible glass solidification device, the pressure control of cold crucible and calciner is very important. However, due to the periodic decomposition or sealing problem of calcined products, there will be large ...
WANG Zexue;LI Baojun;LI Yusong;QIE Dongsheng
doaj