Results 91 to 100 of about 59,071 (329)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Presumption of Innocence and Public Safety: A Possible Dialogue
Stability : International Journal of Security and Development, 2014 In Mexico, increasing demands for public safety coupled with the need for a more effective criminal justice system resulted in the security and justice constitutional reform of 2008. The outcome was a constitutional framework with provisions based on the
Ana Aguilar-Garcia
doaj +1 more source
Immigration Law\u27s Missing Presumption [PDF]
, 2023 The presumption of innocence is a foundational concept in criminal law but is completely missing from quasi-criminal immigration proceedings. This Article explores the relevance of a presumption of innocence to removal proceedings, arguing that ...
Marouf, Fatma
core
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
European Approaches to Fighting Terrorism [PDF]
, 2010 På senare tid har smarta mobila enheter fått en allt större roll i vardagen och det finns en uppsjö av applikationer till dessa. Den som är uppmärksam kan upptäcka att prestandan och användarupplevelsen kan variera kraftigt mellan olika applikationer ...
Van Sliedregt, Elies
core +1 more source
Trumping communitarianism: crime control and forensic DNA typing and databasing in Singapore [PDF]
, 2014 Liberalism and communitarianism have figured prominently in discussions of how to govern forensic DNA practices (forensic DNA typing and databasing). Despite the prominence of these two political philosophies and their underlying values, no studies have ...
Toom, Victor
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Rethinking of Fair Trial in the Light of Balance Principle of Rights of Victim and Accused [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i Kiyfarī, 2015 According to the conventional definition, fair trial is a trial by acompetent tribunal in accordance with procedural guarantees to protect thedefendants’ constitutional and legal rights especially in order to respecthis/her human dignity and presumption ...
Mehrdad Rayijian Asli
doaj