Results 101 to 110 of about 58,278 (391)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
European Approaches to Fighting Terrorism [PDF]
, 2010 På senare tid har smarta mobila enheter fått en allt större roll i vardagen och det finns en uppsjö av applikationer till dessa. Den som är uppmärksam kan upptäcka att prestandan och användarupplevelsen kan variera kraftigt mellan olika applikationer ...
Van Sliedregt, Elies
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Rhetoric of Innocence [PDF]
, 1995 This Article promotes the serious consideration of innocence in the criminal process, and gives meaning to the rhetoric surrounding the presumption of innocence.
Laufer, William S.
core +1 more source
The distinction between the beginning «in dubio pro reo» and the presumption of innocence in spanish criminal procedure [PDF]
, 2014 El presente artículo centra su análisis en uno de los principios de mayor utilización práctica en la justicia penal. Tradicionalmente relacionado con el ámbito de la valoración de las pruebas, en la actualidad el principio «in dubio pro reo» ha ...
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Rethinking of Fair Trial in the Light of Balance Principle of Rights of Victim and Accused [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i Kiyfarī, 2015 According to the conventional definition, fair trial is a trial by acompetent tribunal in accordance with procedural guarantees to protect thedefendants’ constitutional and legal rights especially in order to respecthis/her human dignity and presumption ...
Mehrdad Rayijian Asli
doaj
Formulation of the Statement of Objections , presumption of innocence , due process , principle of lenity , rule of law, military promotion [PDF]
, 2015 El presente trabajo investigativo pretende indagar en el tema “La Formulación de Pliegos de Cargos y el Alcance de la Presunción de Inocencia con Respecto al Ascenso Militar”, el cual se desarrolla a partir del análisis e interpretación constitucional ...
Perez Castro, Raiza Yanira
core