Results 101 to 110 of about 51,789 (323)

Analysis of methodological presumptions for optimisation of marketing programmes

open access: yesBusiness: Theory and Practice, 2013
The analysis focuses on researches on optimisation of marketing programmes conducted over the last decade. On one hand, methods and models suggested by the researchers as well as results obtained by experimental modelling do not comply with contemporary ...
Juozas Bivainis, Irena Daukševičiūtė
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Presumptions for E-leadership in Local Self-Government in Lithuania [PDF]

open access: yesIzzivi Prihodnosti, 2019
Purpose and Originality:ICT usage in management processes became inseparable part of both private and public organizations’ practice. E-leadership concept is quite new in public administration area.
Rita Toleikienė, Vita Juknevičienė
doaj  

Construction Aspects of System for Wireless Low Power Transfer on Moving Parts of Electric Machinery

open access: yesCommunications, 2015
The paper discuses important construction aspects of resonant wireless power transfer (WPT) system for moving parts of electric machinery. It focuses mainly on key electrical parameters of the systems resonant linkage and its simple and durable ...
Vladimir Kindl   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Fallacy of Misplaced Presumption

open access: yesArgumentation, 2023
One takes one's word that p when a source vouches for p and one accepts the word of that source. If the source is reliable in this case, p is acceptable. The reliability of the source is a measure of its plausibility. If a source has the relevant competence, credibility, authority, that word is acceptable.
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Presumptions and Burdens of Proof

open access: yes, 2008
. This paper studies the logical modelling of presumptions and their effects on the burden of proof. Presumptions are modelled as default rules and their effect on the burden of proof is defined in terms of a distinction between the burden of production,
Henry Prakken A, Giovanni Sartor B
core  

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