Differential synaptic depression mediates the therapeutic effect of deep brain stimulation. [PDF]
Li J +7 more
europepmc +1 more source
Upstream CB1R Regulation of β‐Adrenergic Memory Consolidation
ABSTRACT Object recognition memory (ORM) plays a key role in identifying familiar items and encoding episodic information. ORM consolidation depends on β‐adrenergic receptor (βAR) signaling and is associated with increased BDNF expression in the dorsal hippocampus.
Janine I. Rossato +9 more
wiley +1 more source
Age-related ultrastructural differences in the dorsal cortex of the inferior colliculus in the fischer brown Norway rat. [PDF]
Smallridge DZ +12 more
europepmc +1 more source
Deep learning tissue mapping can guide region of interest selection for spatial transcriptomic analyses. Using this method, a transcriptional catalogue of focal cortical dysplasia type IIb was generated, revealing enrichment for markers of inhibitory glycinergic signaling in cytomegalic dysmorphic neurons.
Ameesha Paliwal +8 more
wiley +1 more source
Presynaptic Terminal Proteins and Nicotinic Receptors Are Depleted from Mouse Parasympathetic Ganglionic Junctions Paralysed with Botulinum Neurotoxin Type A. [PDF]
Al-Sabi A, Lawrence GW.
europepmc +1 more source
Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman +4 more
wiley +1 more source
Brain-wide mapping of developmental trajectories of cerebellar efferent projections. [PDF]
Murcia-Ramón R +4 more
europepmc +1 more source
Abstract Neurodegenerative diseases, including debilitating conditions like Alzheimer's and Parkinson's, are characterized by progressive neuronal loss, a process fundamentally driven by persistent chronic neuroinflammation and central metabolic dysfunction.
Renata Spezani +1 more
wiley +1 more source
Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β. [PDF]
Shinno K +4 more
europepmc +1 more source
Synaptic Vesicle Disruption in Parkinson's Disease: Dual Roles of α-Synuclein and Emerging Therapeutic Targets. [PDF]
Treviño M +4 more
europepmc +1 more source

