Results 91 to 100 of about 6,044,805 (317)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Final farewell to Claudio Rapezzi: observation, deduction and knowledge in medicine

Frontiers in Cardiovascular Medicine, 2023
Aldostefano Porcari, Aldostefano Porcari, Aldostefano Porcari, Gianfranco Sinagra, Gianfranco Sinagra, Cristina Candida Quarta, Marianna Fontana, Julian D. Gillmore   +7 more
doaj   +1 more source

Impact of the Noninvasive Diagnostic Algorithm on Clinical Presentation and Prognosis in Cardiac Amyloidosis

JACC: Advances
Background: The introduction of a noninvasive diagnostic algorithm in 2016 led to increased awareness and recognition of cardiac amyloidosis (CA). Objectives: The purpose of this study was to analyze the impact of the introduction of the noninvasive ...
Giacomo Tini, MD, Ernesto Cristiano, MD, Mattia Zampieri, MD, Alberto Ponziani, MD, Aldostefano Porcari, MD, Margherita Zanoletti, MD, Carlotta Mazzoni, MD, Matteo Sclafani, MD, Giulia Saturi, MD, Andrea Lalario, MD, Marianna Eleonora Labate, MD, Camillo Autore, MD, Emanuele Barbato, MD, Federico Perfetto, MD, Elena Biagini, MD, Gianfranco Sinagra, MD, Marco Canepa, MD, Marco Merlo, MD, Simone Longhi, MD, Francesco Cappelli, MD, Beatrice Musumeci, MD   +20 more
doaj   +1 more source

Type 2 diabetes in Tirana City, Albania: a rapid increase in a country in transition.

, 2004
AIMS: To determine how the prevalence of Type 2 diabetes mellitus has changed in Tirana, the capital of Albania, over 20 years. METHODS: Cluster sampling was used to select 700 households including 1540 adults 25 years of age and over in Tirana City ...
Coker, R, McKee, M, Shapo, L, Ylli, A
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Unique Features of Cardiovascular Involvement and Progression in Children with Marfan Syndrome Justify Dedicated Multidisciplinary Care

Journal of Cardiovascular Development and Disease
Marfan syndrome (MIM: # 154700; MFS) is an autosomal dominant disease representing the most common form of heritable connective tissue disorder. The condition presents variable multiorgan expression, typically involving a triad of cardiovascular, eye ...
Anwar Baban, Giovanni Parlapiano, Marianna Cicenia, Michela Armando, Alessio Franceschini, Concettina Pacifico, Arianna Panfili, Gaetano Zinzanella, Antonino Romanzo, Adelaide Fusco, Martina Caiazza, Gianluigi Perri, Lorenzo Galletti, Maria Cristina Digilio, Paola Sabrina Buonuomo, Andrea Bartuli, Antonio Novelli, Massimiliano Raponi, Giuseppe Limongelli   +18 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Venous congestion in a d-TGA patient after Mustard procedure

REC: Interventional Cardiology (English Ed.)
A 45-year-old patient with dextro-transposition of the great arteries (d-TGA) repaired via Mustard procedure at the age of 5 years presented with lower limb venous congestion.
Francisco Javier Ruperti-Repilado, Félix Coserria-Sánchez, Amadeo Wals-Rodríguez, Agustín Guisado, José Díaz-Fernández, Pastora Gallego   +5 more
doaj   +1 more source

Estimating Prevalence, Demographics, and Costs of ME/CFS Using Large Scale Medical Claims Data and Machine Learning

Frontiers in Pediatrics, 2019
Techniques of data mining and machine learning were applied to a large database of medical and facility claims from commercially insured patients to determine the prevalence, gender demographics, and costs for individuals with provider-assigned diagnosis
Ashley R. Valdez, Elizabeth E. Hancock, Seyi Adebayo, David J. Kiernicki, Daniel Proskauer, John R. Attewell, Lucinda Bateman, Alfred DeMaria, Charles W. Lapp, Peter C. Rowe, Charmian Proskauer   +10 more
doaj   +1 more source

A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States [PDF]

, 2021
Vikas Gupta, Kalvin Yu, Jennifer Schranz, Steven P Gelone   +3 more
openalex   +1 more source