Results 101 to 110 of about 6,044,805 (317)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Congestión venosa en paciente con d-TGA tras Mustard

REC: Interventional Cardiology
Este es el caso de un varón de 45 años con dextrotransposición de las grandes arterias (d-TGA) reparada mediante la operación de Mustard a la edad de 5 años con un cuadro de congestión venosa en las extremidades ...
Francisco Javier Ruperti-Repilado, Félix Coserria-Sánchez, Amadeo Wals-Rodríguez, Agustín Guisado, José Díaz-Fernández, Pastora Gallego   +5 more
doaj   +1 more source

Prevalence of positive depression screen among post miscarriage women- A cross sectional study

BMC Psychiatry, 2018
Background Miscarriages are a common pregnancy complication affecting about 10–15% of pregnancies. Miscarriages may be associated with a myriad of psychiatric morbidity at various timelines after the event. Depression has been shown to affect about 10–20%
Steve Kyende Mutiso, Alfred Murage, Abraham Mwaniki Mukaindo   +2 more
doaj   +1 more source

Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study [PDF]

, 2016
Sarah Blach, Stefan Zeuzem, Michael P. Manns, Ibrahim Altraif, Ann‐Sofi Duberg, David Handojo Muljono, Imam Waked, Seyed M Alavian, Mei–Hsuan Lee, Francesco Negro, Faisal Abaalkhail, Ahmed Ms Abdou, Maheeba Abdulla, Antoine Abou Rached, Inka Aho, Ulus Salih Akarca, Imad Ghazzawi, Saad Al Kaabi, Faryal Al Lawati, Khalid Al Namaani, Y. Al Serkal, Said A. Al‐Busafi, L. Al‐Dabal, Soo Aleman, Abdullah Alghamdi, Abdulrahman Aljumah, Hamad Eid Al‐Romaihi, Monique Andersson, Vic Arendt, Perttu Arkkila, Abdullah M. Assiri, Oidov Baatarkhuu, Abate Bane, Ziv Ben‐Ari, Colm Bergin, Fernando Bessone, Florian Bihl, Abdul Rahman Bizri, Martin Blachier, Antonio Javier Blasco, Carlos Eduardo Brandão‐Mello, Philip Bruggmann, Cheryl Brunton, Filipe Calinas, Henry Lik‐Yuen Chan, Asad Chaudhry, Hugo Cheinquer, Chien‐Jen Chen, Rong‐Nan Chien, Moon Seok Choi, Peer Brehm Christensen, Wan‐Long Chuang, Vladimir Chulanov, Laura Cisneros, Mette Rye Clausen, Matthew Cramp, Antonio Craxı̀, Esther A. Croes, Olav Dalgård, Jorge Daruich, Victor de Lédinghen, Gregory J. Dore, Manal H. El‐Sayed, Gül Ergör, Gamal Esmat, Chris Estes, Karolin Falconer, Elmoubasher Farag, Maria Lúcia Gomes Ferraz, Paulo Roberto Abrão Ferreira, Robert Flisiak, Soňa Fraňková, Ivane Gamkrelidze, Ed Gane, Javier García‐Samaniego, Amir Ghafoor Khan, Ilias Gountas, Adrian Goldis, Magnús Gottfreðsson, Jason Grebely, Michael Gschwantler, Mário Guimarães Pessôa, J. Gunter, Behzad Hajarizadeh, O. Hajelssedig, Saeed Hamid, Waseem Hamoudi, Angelos Hatzakis, Sayed Himatt, Harald Hofer, Irena Hrstić, Yee-Tak Hui, Béla Hunyady, Ramazan Idılman, Wasim Jafri, Rohani Jahis, Naveed Z. Janjua, Peter Jarčuška, Agita Jēruma, Jón G. Jónasson   +99 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Appropriate time interval to update ambiguous genetic diagnosis in inherited arrhythmogenic syndromes

iScience
Summary: Genetic analysis identified the cause of the disease in inherited arrhythmogenic syndromes. A clinically actionable genetic diagnosis requires an accurate interpretation following the current guidelines. Practically half of the genetic diagnoses
Estefanía Martínez-Barrios, Andrea Greco, Sergi Cesar, Carles Díez-López, José Cruzalegui, Nuria Díez-Escuté, Patricia Cerralbo, Fredy Chipa, Irene Zschaeck, Simone Grassi, Antonio Oliva, Norma Balderrábano, Rocío Toro, Georgia Sarquella-Brugada, Oscar Campuzano   +14 more
doaj   +1 more source

A survey of the prevalence of Schistosomiasis among pupils in Apata and Laranto areas in Jos, Plateau State [PDF]

, 2004
Prevalence of Schistosomiasis in apparently healthy primary school pupils in Apata and Laranto areas of Jos was surveyed using 300 samples of stool and 300 samples of urine.
Agba Ikenna, Dr. Matthias, Chimezie Remigius, Onyirioha, Ezera, Agwu, Nwobu Obiora, Dr. Gilbert, Ohihoin Abuovbo, Aidevbo, Okpala Obi, Herbert   +5 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The contribution of genetics to the understanding and management of cardiomyopathies: Part 2

Revista Portuguesa de Cardiologia
Cardiomyopathies may present as a manifestation of various inherited syndromes. Recognizing the rarity and diagnostic challenges of syndromic and metabolic cardiomyopathies is crucial, as their identification holds significant implications for targeted ...
Isabel Cardoso, Mafalda Melo, Pedro Brás, José Miguel Viegas, Inês Almeida, Sofia Nunes, Inês Custódio, Conceição Trigo, Sérgio Laranjo, Rafael Graça, Rui Cruz Ferreira, Mário Oliveira, Sílvia Aguiar Rosa, Diana Antunes   +13 more
doaj   +1 more source

Impact of antiretroviral therapy on adult HIV prevalence in a low-income rural setting in Uganda: a longitudinal population-based study.

, 2013
OBJECTIVE: To estimate the contribution to HIV prevalence of lives saved due to the introduction of antiretroviral therapy (ART) in rural Uganda in 2004. DESIGN: Open population-based cohort study.
Maher, Dermot, Nsubuga, Rebecca N, Todd, Jim E   +2 more
core   +1 more source