Results 111 to 120 of about 6,044,805 (317)

Guidelines for evaluating prevalence studies [PDF]

, 1998
Michael H. Boyle
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Cognitive Improvement After Stroke: Prevalence and Trend During the First Three Months

Cerebral Circulation - Cognition and Behavior
Introduction: With similar estimates at 3 and 12 months after stroke, 4 out of 10 individuals have cognitive impairment that does not match the criteria for dementia.
Maede Sadat Etesami, Jūratė Šaltytė Benth, Elisabeth Kliem, Siri Weider, Knut Hestad, Ramune Grambaite   +5 more
doaj   +1 more source

Prevalence and risk factors for peripheral neuropathy among type 2 diabetes mellitus patients at a tertiary care hospital in coastal Karnataka

Indian Journal of Endocrinology and Metabolism, 2017
Context and Objective: In view of the growing burden of type 2 diabetes mellitus (T2DM) globally and associated microvascular and macrovascular complications, the study was done to assess the prevalence and risk factors for diabetic neuropathy among T2DM
Sonalika Gogia, Chythra R Rao
doaj   +1 more source

Human papillomavirus prevalence and type distribution in invasive cervical cancer in sub‐Saharan Africa [PDF]

, 2013
Lynette Denny, Isaac F. Adewole, Rose Anorlu, Greta Dreyer, Manivasan Moodley, Trudy Smith, Leon Snyman, Edwin K. Wiredu, Anco Molijn, Wim Quint, Gunasekaran Ramakrishnan, Johannes Schmidt   +11 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Blood Biomarkers Predict 10-Year Clinical Outcomes in Adult Patients With Congenital Heart Disease

JACC: Advances
Background: The adult congenital heart disease (ACHD) population is growing and risk prediction is important to predict adverse outcome and consult patients during their lifecourse.
Paul M. Hendriks, MSc, MD, Annemien E. van den Bosch, MD, PhD, Laurie W. Geenen, MSc, MD, PhD, Vivan J.M. Baggen, MD, PhD, Jannet A. Eindhoven, MD, PhD, Robert M. Kauling, MD, Judith A.A.E. Cuypers, MD, PhD, Eric Boersma, PhD, Jolien W. Roos-Hesselink, MD, PhD   +8 more
doaj   +1 more source

Toric implantable collamer lens for keratoconus

Indian Journal of Ophthalmology, 2013
Keratoconus is a progressive non-inflammatory thinning of the cornea that induces myopia and irregular astigmatism and decreases the quality of vision due to monocular diplopia, halos, or ghost images.
Mathew Kurian Kummelil, M S Hemamalini, Ridhima Bhagali, Koushik Sargod, Somshekar Nagappa, Rohit Shetty, Bhujang K Shetty   +6 more
doaj   +1 more source

Influence of race/ethnicity on prevalence and presentation of endometriosis: a systematic review and meta‐analysis [PDF]

, 2019
Olga Bougie, Ma.I Yap, Lindsey Sikora, Teresa E. Flaxman, Sukhbir S. Singh   +4 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source