Results 81 to 90 of about 6,109,166 (291)

Cardiac Resynchronization Therapy, Remodeling, and Outcome in Patients With Amyloid Transthyretin Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Transthyretin amyloid cardiomyopathy (ATTR‐CM) has a specific pathophysiology, with myocardial stiffening and systolic dysfunction only in advanced stages. We aimed to investigate the response to cardiac resynchronization therapy (CRT) in ATTR‐
Alberto Aimo, Martina Nesti, Giuseppe Vergaro, Ammar M. Killu, Dimitrios Bampatsias, Daniela Tomasoni, Cinzia Forleo, Francesco Musca, Matteo Serenelli, Julie Rosenthal, Sergio L. Teruya, Nader J. Al‐Shakarchi, Mariel S. Tameze, Vincenzo Castiglione, Alessio Nicolai, Giorgia Panichella, Riccardo Saro, Aldostefano Porcari, Giulio Sinigiani, Vera Fico, Elisa Frau, Reem Matar, Andrea I. Guaricci, Giacomo Tini, Alberto Cipriani, Maria B. Musumeci, Simone Longhi, Cristina Chimenti, Marco Metra, Martha Grogan, Federico Perfetto, Francesco Cappelli, Marco Merlo, Gianfranco Sinagra, Mathew S. Maurer, Ahmad Masri, Michele Emdin   +36 more
doaj   +1 more source

Spatial mapping of hepatitis C prevalence in recent injecting drug users in contact with services. [PDF]

, 2011
In developed countries the majority of hepatitis C virus (HCV) infections occur in injecting drug users (IDUs) with prevalence in IDUs often high, but with wide geographical differences within countries.
A. MORONGIU, Bajekal, Brooks, D. DE ANGELIS, F. NCUBE, Ghangurde, Hope, Hope, Kelsall, M. HICKMAN, Martin, R. J. HARRIS, Spiegelhalter, V. D. HOPE   +13 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

A systematic review and meta-analysis on the prevalence of dementia in europe. estimates from the highest-quality studies adopting the dsm iv diagnostic criteria [PDF]

, 2018
BACKGROUND: Dementia, including Alzheimer's disease (AD), is one of the most burdensome medical conditions. Usually, the reviews that aim at calculating the prevalence of dementia include estimates from studies without assessing their methodological ...
Bacigalupo, I, Canevelli, M, Di Fiandra, T, Di Pucchio, A, Lacorte, E, Marzolini, F, Mayer, F, Vanacore, N.   +7 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Incidence, prevalence, and global burden of autism spectrum disorder from 1990 to 2019 across 204 countries

, 2022
Marco Solmi, Minjin Song, Dong Keon Yon, Seung Won Lee, Éric Fombonne, Min Seo Kim, Seoyeon Park, Min Ho Lee, Jimin Hwang, Roberto Keller, Ai Koyanagi, Louis Jacob, Elena Dragioti, Lee Smith, Christoph U. Correll, Paolo Fusar‐Poli, Giovanni Croatto, André F. Carvalho, Jae Won Oh, San Lee, Corentin J. Gosling, Keun‐Ah Cheon, Dimitris Mavridis, Che‐Sheng Chu, Chih‐Sung Liang, Joaquim Raduà, Laurent Boyer, Guillaume Fond, Jae Il Shin, Samuele Cortese   +29 more
openalex   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Final farewell to Claudio Rapezzi: observation, deduction and knowledge in medicine

Frontiers in Cardiovascular Medicine, 2023
Aldostefano Porcari, Aldostefano Porcari, Aldostefano Porcari, Gianfranco Sinagra, Gianfranco Sinagra, Cristina Candida Quarta, Marianna Fontana, Julian D. Gillmore   +7 more
doaj   +1 more source

Impact of the Noninvasive Diagnostic Algorithm on Clinical Presentation and Prognosis in Cardiac Amyloidosis

JACC: Advances
Background: The introduction of a noninvasive diagnostic algorithm in 2016 led to increased awareness and recognition of cardiac amyloidosis (CA). Objectives: The purpose of this study was to analyze the impact of the introduction of the noninvasive ...
Giacomo Tini, MD, Ernesto Cristiano, MD, Mattia Zampieri, MD, Alberto Ponziani, MD, Aldostefano Porcari, MD, Margherita Zanoletti, MD, Carlotta Mazzoni, MD, Matteo Sclafani, MD, Giulia Saturi, MD, Andrea Lalario, MD, Marianna Eleonora Labate, MD, Camillo Autore, MD, Emanuele Barbato, MD, Federico Perfetto, MD, Elena Biagini, MD, Gianfranco Sinagra, MD, Marco Canepa, MD, Marco Merlo, MD, Simone Longhi, MD, Francesco Cappelli, MD, Beatrice Musumeci, MD   +20 more
doaj   +1 more source

The relationship of dementia prevalence in older adults with intellectual disability (ID) to age and severity of ID [PDF]

, 2009
Background: Previous research has shown that adults with intellectual disability (ID) may be more at risk of developing dementia in old age than expected. However, the effect of age and ID severity on dementia prevalence rates has never been reported. We
Hassiotis, A., King, M., Livingston, G., Strydom, A.   +3 more
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