Results 81 to 90 of about 7,501,773 (380)

Point prevalence survey of antimicrobial use and healthcare-associated infections in Belgian acute care hospitals: results of the Global-PPS and ECDC-PPS 2017

Antimicrobial Resistance and Infection Control, 2020
Background The point prevalence survey of healthcare-associated infections (HAIs) and antimicrobial use organized by the European Centre for Disease Prevention and Control (ECDC-PPS) and the Global Point Prevalence Survey of antimicrobial consumption ...
Eline Vandael, Katrien Latour, Herman Goossens, Koen Magerman, Nico Drapier, Boudewijn Catry, Ann Versporten, the Belgian Point Prevalence Survey Study Group   +7 more
doaj   +1 more source

Increasing prevalence of asthma diagnosis and symptoms in children is confined to mild symptoms [PDF]

, 2001
BACKGROUND: The prevalence of childhood asthma is increasing but few studies have investigated trends in asthma severity. We investigated trends in asthma diagnosis and symptom morbidity between an eight year time period in a paired prevalence study.
Billings, C., Das, C., Duggan, R., Ng Man Kwong, G., Powell, C.V.E., Primhak, R.A., Proctor, A., Whyte, M.K.B.   +7 more
core   +2 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Clinical Features and Outcomes of Pediatric MYH7‐Related Dilated Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Although genetic variants in MYH7 are the most frequent cause of pediatric genetic dilated cardiomyopathy (DCM), there are no studies available describing this entity.
Fernando de Frutos, Juan Pablo Ochoa, Gregory Webster, Mark Jansen, Paloma Remior, Torsten B. Rasmussen, Maria Sabater‐Molina, Roberto Barriales‐Villa, Francesca Girolami, Sergi Cesar, M. Eugenia Fuentes‐Cañamero, Reyes Alvarez García‐Rovés, Karim Wahbi, Javier Limeres, Milos Kubanek, Martijn G. Slieker, Georgia Sarquella‐Brugada, Dominic J. Abrams, Dennis Dooijes, Fernando Domínguez, Pablo Garcia‐Pavia   +20 more
doaj   +1 more source

Prevalence and incidence [PDF]

BMJ, 2010
A randomised controlled trial investigated whether screening and treating women for chlamydial infection reduced the subsequent occurrence of pelvic inflammatory disease.1 Between 2004 and 2006, vaginal swabs were provided by 2529 sexually active female students. The samples were randomly allocated to immediate testing (screening group), or storage and
openaire   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Long-Term Outcome After Mustard Repair at Young Age

JACC: Advances
Background: Concerns remain regarding the high incidence of morbidity in transposition of the great arteries (TGA) patients who underwent Mustard repair.
Sahra Ünlütürk, MD, Robert M. Kauling, MD, Judith A.A.E. Cuypers, MD, PhD, Annemien E. van den Bosch, MD, PhD, Alexander Hirsch, MD, PhD, Mieke M.P. Driessen, MD, PhD, Chiara Pelosi, MD, PhD, Daniel J. Bowen, PhD, Ad J.J.C. Bogers, MD, PhD, Willem A. Helbing, MD, PhD, Isabella Kardys, MD PhD, Jolien W. Roos-Hesselink, MD, PhD   +11 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Generation of iPSC lines (ICHi001-A, ICHi002-A, ICHi003-A, ICHi004-A) from four patients carrying Titin truncating variants associated with dilated cardiomyopathy

Stem Cell Research
Inherited dilated cardiomyopathy (iDCM) is a disease of the heart muscle, characterized by left ventricle enlargement, systolic dysfunction and arrhythmias.
Cecilia Thairi, Rebecca Artioli, Marianna Paulis, Camilla Galli, Simon Cotič, Alessia Paldino, Ilenia Marino, Gianfranco Sinagra, Chiara Collesi, Matteo Dal Ferro, Elisa Di Pasquale   +10 more
doaj   +1 more source

Goitre and Iodine Deficiency in Europe [PDF]

, 1985
The prevalence of endemic iodine-deficiency goitre in Europe has been reduced in many areas by the introduction of iodination programmes. Recent reports, however, show that goitre remains a significant problem and that its prevalence has not decreased in
Beckers, C., Bürgi, H., Escobar del Rey, F., Gembicki, M., Koutras, D. A., Lamberg, B. A., Langer, P., Lazarus, J. H., Querido, A., Scriba, Peter Christian, Thilly, C., Vigneri, R.   +11 more
core   +1 more source