Results 81 to 90 of about 5,972,282 (290)

Global Economic Expansion and the Prevalence of Militarized Interstate Disputes [PDF]

, 2016
Over the past several decades the entire world has experienced both the positive and negative effects of globalization. The question that this report will address is whether or not global economic expansion has led to a decline in the prevalence of ...
Hahn, Lucas
core   +1 more source

Prevalence and risk factors for hypertension and association with ethnicity in Nigeria: results from a national survey. [PDF]

, 2013
OBJECTIVE: Non-communicable diseases are now a global priority. We report on the prevalence of hypertension and its risk factors, including ethnicity, in a nationally representative sample of Nigerian adults recruited to a survey of visual impairment ...
Entekume, Gabriel, Fox, Samantha, Gilbert, Clare E, Imam, Abdullahi U, Mahdi, Abdull M, Murthy, Gudlavalleti VS, Nigeria National Blindness and Visual Impairment study group, Sivasubramaniam, Selvaraj   +7 more
core   +1 more source

Anxiety and posttraumatic stress in post-acute sequelae of COVID-19: prevalence, characteristics, comorbidity, and clinical correlates [PDF]

, 2023
Stephen J. Ferrando, Sean Lynch, Nicole Ferrando, Rhea Dornbush, Sivan Shahar, Lidia Klepacz   +5 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Impact of the Noninvasive Diagnostic Algorithm on Clinical Presentation and Prognosis in Cardiac Amyloidosis

JACC: Advances
Background: The introduction of a noninvasive diagnostic algorithm in 2016 led to increased awareness and recognition of cardiac amyloidosis (CA). Objectives: The purpose of this study was to analyze the impact of the introduction of the noninvasive ...
Giacomo Tini, MD, Ernesto Cristiano, MD, Mattia Zampieri, MD, Alberto Ponziani, MD, Aldostefano Porcari, MD, Margherita Zanoletti, MD, Carlotta Mazzoni, MD, Matteo Sclafani, MD, Giulia Saturi, MD, Andrea Lalario, MD, Marianna Eleonora Labate, MD, Camillo Autore, MD, Emanuele Barbato, MD, Federico Perfetto, MD, Elena Biagini, MD, Gianfranco Sinagra, MD, Marco Canepa, MD, Marco Merlo, MD, Simone Longhi, MD, Francesco Cappelli, MD, Beatrice Musumeci, MD   +20 more
doaj   +1 more source

Rapid assessment for prioritisation of trachoma control at community level in one district of the Kaolack Region, Senegal.

, 2005
The objective of this study was to use a modified Lot Quality Assurance Sampling methodology to classify communities according to prevalence of active trachoma and to estimate the prevalence of trachoma and trichiasis in Nioro department, Kaolack Region,
Bailey, Robin, Dineen, Brendan, Faye, Marcel, Kuper, Hannah   +3 more
core   +1 more source

Prevalence of drooling, swallowing, and feeding problems in cerebral palsy across the lifespan: a systematic review and meta‐analyses [PDF]

, 2019
Aim: To determine the prevalence of drooling, swallowing, and feeding problems in persons with cerebral palsy (CP) across the lifespan. Method: A systematic review was conducted using five different databases (AMED, CINAHL, Embase, MEDLINE, and PubMed ...
Bakarčić D, Morales‐Chávez M, Rodrigues dos Santos MTB, Rosenbaum P, Sedky NA, Strauss D, US Institute of Medicine Committee on Regional Health Data Networks, Wilson EM   +7 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Unique Features of Cardiovascular Involvement and Progression in Children with Marfan Syndrome Justify Dedicated Multidisciplinary Care

Journal of Cardiovascular Development and Disease
Marfan syndrome (MIM: # 154700; MFS) is an autosomal dominant disease representing the most common form of heritable connective tissue disorder. The condition presents variable multiorgan expression, typically involving a triad of cardiovascular, eye ...
Anwar Baban, Giovanni Parlapiano, Marianna Cicenia, Michela Armando, Alessio Franceschini, Concettina Pacifico, Arianna Panfili, Gaetano Zinzanella, Antonino Romanzo, Adelaide Fusco, Martina Caiazza, Gianluigi Perri, Lorenzo Galletti, Maria Cristina Digilio, Paola Sabrina Buonuomo, Andrea Bartuli, Antonio Novelli, Massimiliano Raponi, Giuseppe Limongelli   +18 more
doaj   +1 more source