Results 151 to 160 of about 6,466,594 (289)

Human and organizational factors within the public sectors for the prevention and control of epidemic

, 2020
Lipeng Fu, Xueqing Wang, Dan Wang, Mark Griffin, Peixuan Li   +4 more
openalex   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Drivers of change in weight‐for‐height among children under 5 years of age in Ethiopia: Risk factors and data gaps to identify risk factors

Maternal and Child Nutrition
The prevention of wasting should be a public health priority as the global burden of acute malnutrition is still high. Gaps still exist in our understanding of context‐specific risk factors and interventions that can be implemented to prevent acute ...
Meron Girma, Alemayehu Hussein, Kaleab Baye, Aregash Samuel, Cornelia vanZyl, Masresha Tessema, Stanley Chitekwe, Arnaud Laillou   +7 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

A brief history of the development of infectious disease prevention, control, and biosafety programs in China

, 2020
Liang Huigang, Xiang Xiaowei, Cui Huang, MA Hai-xia, Zhiming Yuan   +4 more
openalex   +1 more source

An Outpatient Multifactorial Falls Prevention Intervention Does Not Reduce Falls in High‐Risk Elderly Danes [PDF]

, 2009
Ane Bonnerup Vind, Hanne Elkjær Andersen, Kirsten Damgaard Pedersen, Torben Jørgensen, Peter Schwarz   +4 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7

, 2009
Tomoko Hayashi, Christine S. Gray, Michael Chan, Rommel I. Tawatao, Lisa Ronacher, Maureen A. McGargill, Sandip K. Datta, Dennis A. Carson, Maripat Corr   +8 more
openalex   +1 more source

Stakeholders’ participation in planning and priority setting in the context of a decentralised health care system: the case of prevention of mother to child transmission of HIV programme in Tanzania [PDF]

, 2013
Elizabeth H. Shayo, Leonard E. G. Mboera, Astrid Blystad   +2 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source