Results 71 to 80 of about 610,493 (255)

Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells

Molecular Cancer, 2010
Background Sulforaphane (SFN), an isothiocyanate phytochemical present predominantly in cruciferous vegetables such as brussels sprout and broccoli, is considered a promising chemo-preventive agent against cancer.
Morris Robert, Qazi Aamer M, Seward Shelly, Haider Mahdi, Pal Jagannath, Shah Jay, Chamala Sreedhar, Kumar Sanjeev, Bryant Christopher S, Semaan Assaad, Shammas Masood A, Steffes Christopher, Potti Ravindra B, Prasad Madhu, Weaver Donald W, Batchu Ramesh B   +15 more
doaj   +1 more source

Update on prevention and treatment of sudden cardiac arrest

Trends in Cardiovascular Medicine, 2019
Sudden cardiac arrest is the leading cause of cardiovascular mortality, posing a substantial public health burden. The incidence and epidemiology of sudden death are a function of age, with primary arrhythmia syndromes and inherited cardiomyopathies representing the predominant causes in younger patients, while coronary artery disease being the leading
Krokhaleva, Yuliya, Vaseghi, Marmar
openaire   +5 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The feasibility of performing a randomised controlled trial of therapeutic hypothermia for neuroprotection after paediatric cardiac arrest in the UK [PDF]

Cardiac arrest in paediatric patients often results in death or survival with severe brain injury. Therapeutic hypothermia, lowering of core body temperature to 32 to 34⁰C may reduce injury to the brain in the period after circulation has been restored.
Scholefield, Barnaby R.
core  

Screening for Hepatitis B Virus Infection in Pregnant Women: US Preventive Services Task Force Reaffirmation Recommendation Statement [PDF]

, 2019
Full author list omitted for brevity. For the full list of authors, see article.Importance: Screening for hepatitis B virus (HBV) infection during pregnancy identifies women whose infants are at risk of perinatal transmission.
Pbert, Lori, Owens, Douglas K., US Preventive Services Task Force   +2 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Arrestees Substance Abuse: Moving Toward Rehabilitation Camps or Prisons

Iranian Rehabilitation Journal, 2020
Objectives: Illicit drug abuse and drug-related crimes are still a growing problem worldwide. Understanding the increasing number of individuals arrested for drug charges, as well as their characteristics is necessary to predict and establish preventive ...
Fahimeh Mohseni, Elie Moghimi Khorasani, Ali Asghar Nadi Ghara, Raheleh Rafaiee   +3 more
doaj  

Blocking Variant Surface Glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation [PDF]

, 2009
Background: The African trypanosome Trypanosoma brucei is covered with a dense layer of Variant Surface Glycoprotein (VSG), which protects it from lysis by host complement via the alternative pathway in the mammalian bloodstream.
Gluenz, E, Rudenko, G, Gluenz Eva, Terry K Smith, Shulamit Michaeli, Susanne Kramer, Michaeli, Shulamit, Terry, Stephen, Terry K. Smith, Michaeli, S, Eva Gluenz, Smith, Terry K., Vasileva, N, Nadina Vasileva, Mark Carrington, Michaeli Shulamit, Vasileva, Nadina, Carrington, M, Stephen Terry, Rudenko Gloria, Gull Keith, Portman, N, Gluenz, Eva, Keith Gull, Terry, S, Smith Terry K., Neil Portman, Gull, K, Kramer, S, Portman, Neil, Smith, TK, Smith, Terry K, Rudenko, Gloria, Terry Stephen, Vasileva Nadina, Gull, Keith, Carrington Mark, Carrington, Mark, Kramer, Susanne, Terry K. Smith, Portman Neil, Kramer Susanne, Gloria Rudenko   +42 more
core   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Cardiac arrest: Treatment is prevention?

Resuscitation
The management of cardiac arrest has benefited from recent advances in cardiopulmonary resuscitation techniques. However, despite improvements, the incidence of sudden cardiac death is still high, with more than 4.1 deaths per 100,000 person-years in the United States, and continues to have very low survival rates at hospital discharge - 8% on average -
Descatha, Alexis, Savary, Dominique
openaire   +3 more sources