Results 71 to 80 of about 125,549 (303)

Risk Assessments for Chemical Stockpile Incinerators: Is the Supporting Guidance Adequate [PDF]

open access: yes, 2000
The author identifies potential deficiencies in guidance used in the United States for risk assessments of chemical weapons ...
Tannenbaum, Lawrence V.
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

LarvaTracing : Imagerie RMN des infestations dans les œuvres d’art en bois et matériaux organiques

open access: yesIn Situ, 2019
The infestation of a work of art may be destructive for the piece itself and also presents the threat of spreading throughout an entire collection. Several methods are available to museums in order to diagnose an infestation at an early stage and then ...
Grazia Nicosia   +4 more
doaj   +1 more source

Delinquency Prevention through Crime Conservation

open access: yesJournal of Politics and Law, 2016
<p>Nowadays, the prevention of crime over the past are subjected to the judicial authorities seriously and criminal policy has adopted a set of measures to deal with criminal phenomenon that a part of the measures returns to situational prevention measures which seeks to limit the opportunities and situations causing offense and makes difficult ...
Ahlam Mohammadi   +1 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Methodological Reflexions on Preventive Conservation [PDF]

open access: yes, 2013
Se presenta una ponencia con unas reflexiones generales sobre los cambios que actualmente se están produciendo en el ámbito de la conservación preventiva, al configurarse como disciplina y el desarrollo de la teoría, la historia y la práxis.
Ruiz-de-Lacanal, María-Dolores
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Tracking Moisture Dynamics in a Karst Rock Formation Combining Multi-Frequency 3D GPR Data: A Strategy for Protecting the Polychrome Hall Paintings in Altamira Cave

open access: yesRemote Sensing
This study addresses the features of the internal structure of the geological layers adjacent to the Polychrome Hall ceiling of the Cave of Altamira (Spain) and their link to the distribution of moisture and geological discontinuities mainly as fractures,
Vicente Bayarri   +4 more
doaj   +1 more source

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